Dear Colleagues, Please note that the following Statistical Conferences will take place in Washington DC. Title: Statistical Issues in Drug Development Content: A Two-day Intensive course avoiding technical detail and concentrating on PRACTICAL and PHILOSOPHICAL issues that determine which data are collected, how the study should be organized, and what the outcome means. It will ensure that participants acquire a well grounded appreciation of the all the important statistical issues surrounding Drug Development. Date: 14 & 15 June 2001 Venue: Georgetown University Conference Center, Washington DC Course Leader: Professor Stephen Senn, University College London, UK Speakers: Professor Peter Lachenbruch, Director of Biostatistics, CBER, US Food and Drug Administration Dr Richard Simon, Head of Molecular Statistics and Bioinformatics, National Cancer Institute, NIH ALL DELEGATES RECEIVE A FREE HARDBACK COPY OF "STATISTICAL ISSUES IN DRUG DEVELOPMENT" BY AUTHOR AND COURSE DIRECTOR Professor STEPHEN SENN Title: Statistics of Optimal Dosing Content: Many statisticians feel that dose selection is very poorly done. This briefing will cover methods appropriate for establishing the "optimal dose". It will examine the problems of dosing and suggest practical solutions. Dose assessment must be done correctly: if assessed incorrectly the cost project delay and extra costs can be very high. Venue: Washington DC, USA Date: 26th July 2001 Title: Statistics of Multi-center Trials Content: Views differ enormously on how multi-center trials should be designed and data from them analyzed. Section 3.2 of the ICH guideline, which has now been adopted in the US, Europe and Japan is open to interpretation. The FDA provides specific guidelines for a strong statistical basis for the design and analysis of clinical trials. Clare Gnecco, Senior Biostatistician, CBER, US FDA will discuss along with other experts, the statistical issues surrounding multi-center trials Venue: Washington DC, USA Date: 14th September 2001 For more information, please got to our website at www.henrystewart.co.uk or contact Dr Carlos Horkan Henry Stewart Conference Studies Russell House 28-30 Little Russell Street London WC1A 2HN Tel: +44 207 404 3040 Fax: +44 207 404 2081 Email: [EMAIL PROTECTED] -- Frank E Harrell Jr Prof. of Biostatistics & Statistics Div. of Biostatistics & Epidem. Dept. of Health Evaluation Sciences U. Virginia School of Medicine http://hesweb1.med.virginia.edu/biostat ================================================================= Instructions for joining and leaving this list and remarks about the problem of INAPPROPRIATE MESSAGES are available at http://jse.stat.ncsu.edu/ =================================================================
