I have to summarize the results of some clinical trials.
Unfortunately the reported information is not complete.
The information given in the trials contain:
(1) Mean effect in the treatment group (days of hospitalization)
(2) Mean effect in the control group (days of hospitalization)
(3) Numbers of patients in the control and treatment group
(4) p-values of a t-test (between the differences of treatment
and control)
My question:
How can I calculate the variance of treatment difference which I need
to perform meta-analysis? Note that the numbers of patients in the
control and treatment group are not equal. Is it possible to do it
like this
s^2 = (difference between contr and treatm in days)^2/ (1/n1+1/n2)*
t^2
How exact would such an approximation be?
I now that meta-analysis is a complex thing and my abilities in
statistics are limited.
Many thanks for your help.
Marc, Germany
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