Dave --

If you "can't control it, then measure it" and include it in your model.
That's the VALUE of using RERESSION/LINEAR MODELS for your analyses.

-- Joe

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Joe H. Ward, Jr.
167 East Arrowhead Dr.
San Antonio, TX 78228-2402
Phone: 210-433-6575
Fax:     210-433-2828
Email:  [EMAIL PROTECTED]
http://www.northside.isd.tenet.edu/healthww/biostatistics/wardindex
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----- Original Message ----- 
From: "Jos Jansen" <[EMAIL PROTECTED]>
To: <[EMAIL PROTECTED]>
Sent: Tuesday, August 19, 2003 8:58 AM
Subject: Re: Exp. design: Controlling for an unknown variable


> "Dave Jeffries" <[EMAIL PROTECTED]> schreef in bericht
> news:[EMAIL PROTECTED]
> > Hi there everyone,
> >
> > I'm trying to set up the analysis for some water research, and I'm
> > hoping to elicit some advice.  So far the bulk is a 2 or 3 factorial
> > design (to be decided later) with no interaction expected.  However,
> > there is one other variable that I can't control - as I said, it's
> > water research, and each sample will be collected discretely, albeit
> > from the same source, but on different days.  There is NO WAY to
> take
> > multiple samples at the same time and store some for later analysis,
> > as each treatment/test will take over 48 hours to run, and the
> sample
> > would change anyway.  While I don't expect any significant changes
> in
> > the samples collected before each test, I need to confirm it.
> >
> > So far, the best method I could come up with is to have a control
> > treatment, one that is run every 3 or 4 treatments throughout the
> > entire experiment, and then do a run-test on the response from it.
> > Then, if the responses are close enough to be accepted as statis.
> > insignificant, just assume that there was no change through the
> other
> > tests as well.
> >
> > However, what I'd like to do is find a more robust method that works
> > the last bit into the factorial design, perhaps through replication,
> > but without letting the number of tests required get to large.  If
> > there's anyone out there who might be able to come up with some idea
> > of how to check this uncontrollable variable, I'd greatly appreciate
> > your thoughts on the matter.
> >
> 
> The traditional way of handling uncontrollable variation is to
> randomize treatments over experimental units, i.c. days. Variation
> between days will thus be contained in your estimate of residual
> variance, which subsequently will be used for estimating the precision
> of treatment effects.
> 
> .
> .
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