Hello Prabhu,

Use this in B2 & copy down. 

=IF(ISNUMBER(SEARCH("Opt. ",A2)),LOOKUP(2,1/ISERROR(SEARCH("Opt. 
",A$2:A2)),A$2:A2)&SUBSTITUTE(A2,"Opt. ","#"),A2)

Then copy Col_B *Paste Values *in Col_A. Then after delete Col_B.

HTH
Haseeb

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