I'm running ClamAV and SpamAssassin (no learning/bayes stuff) for 50k users
split up among three servers (dual xeon 2.4, 2gb ram) and they process/block
lots of email (not sure of the messages/day though).  I've seen load come
close to a 1.0 at peak hours but that's about it.  My configs have quite a
bit of ACL work too - a few db files to check each time, some plain text
white/black list files, etc...

Queues average 30 msgs (deferred outbound) - these systems run pretty mint
:)



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