Here's the article I was talking about:

http://www.personalmd.com/news/n0329052854.shtml


Doctors advise against vitamin C with cancer therapy

  Taking high doses of vitamin C while undergoing traditional cancer 
therapy may interfere with radiation or chemotherapy treatments and 
possibly protect the very cancer cells the treatments are designed to 
destroy, doctors said on Monday.

  Vitamin C, also called ascorbic acid, has long been taken by healthy 
people as well as those who are ill in hopes that its antioxidant 
properties will halt harmful substances in the body known as free 
radicals.

  Taking supplemental tablets of vitamin C is just one of many 
alternative and complementary therapies that cancer patients turn to, 
either out of desperation or simply in a desire to feel better. A high 
dosage of vitamin C would be roughly 1,000 milligrams a day, 
researchers note.

  Dr. David Golde, physician-in-chief at Memorial Sloan-Kettering Cancer 
Center in New York, said that while it is not unreasonable for healthy 
people to supplement their diets with vitamin C, they should be aware 
that most tumors are known to possess a high concentration of the 
chemical already.

  "We don't know what the cancer cell is doing with the vitamin C," 
Golde said. "My experience as a biologist would suggest that it's no 
accident." The use of vitamin C as an alternative therapy has been 
coming back into vogue after a hiatus following a study by Mayo Clinic 
researchers that showed it had no benefit, said Barrie Cassileth, head 
of the Integrative Medicine Service at Memorial Sloan-Kettering.

  Cassileth and Golde were speaking at an annual seminar here sponsored 
by the American Cancer Society.

  Golde and colleagues originally published data on how cells amass high 
concentrations of vitamin C in 1993 and again late last year. Their 
latest research showed cancer cells transport a version of vitamin C 
called dehydroascorbic acid through cellular channels normally used to 
admit the energy source glucose. Cancer cells are also known to have 
many more glucose transport channels than normal cells, which may help 
provide them with the energy the need to thrive.

  "Overall, we need to think about the nutritional needs of tumor cells, 
as well as those of normal cells, in formulating answers to patient 
questions regarding taking supplemental vitamin C," he said. Also, 
because radiation and chemotherapy rely on oxidation to kill cancer 
cells, taking an antioxidant -- such as vitamin C -- may interfere with 
that process.

  While prudent advice for cancer patients is to have very good eating 
habits, Cassileth said alternative therapies that have not been 
adequately studied may in fact be harmful. She said patients may 
inadvertently interfere with their treatment, with anaesthetic agents 
and even trigger cardiac arrest. "That's the last thing we want to 
happen in oncology," she said



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