Michael, the AMA also says that GMO labeling is not necessary. Thus I will look 
askance at anything they publish, no matter how scientific and objective it 
appears to be.







On Thursday, March 20, 2014 9:24 AM, Michael Jackson <mjackso...@yahoo.com> 
wrote:
 
  
Meditation Programs for Psychological Stress and Well-being

A Systematic Review and Meta-analysis

Madhav Goyal, MD, MPH1; Sonal Singh, MD, MPH1; Erica M. S. Sibinga, MD, MHS2; 
Neda F. Gould, PhD3; Anastasia Rowland-Seymour, MD1; Ritu Sharma, BSc4; Zackary 
Berger, MD, PhD1; Dana Sleicher, MS, MPH3; David D. Maron, MHS4; Hasan M. 
Shihab, MBChB, MPH4; Padmini D. Ranasinghe, MD, MPH1; Shauna Linn, BA4; Shonali 
Saha, MD2; Eric B. Bass, MD, MPH1,4; Jennifer A. Haythornthwaite, PhD3

JAMA Intern Med. 2014;174(3):357-368. doi:10.1001/jamainternmed.2013.13018.

ABSTRACT

Importance 
Many people meditate to reduce psychological stress and stress-related health 
problems. To counsel people appropriately, clinicians need to know what the 
evidence says about the health benefits of meditation.

Objective 
To determine the efficacy of meditation programs in improving stress-related 
outcomes (anxiety, depression, stress/distress, positive mood, mental 
health–related quality of life, attention, substance use, eating habits, sleep, 
pain, and weight) in diverse adult clinical populations.

Evidence Review 
We identified randomized clinical trials with active controls for placebo 
effects through November 2012 from MEDLINE, PsycINFO, EMBASE, PsycArticles, 
Scopus, CINAHL, AMED, the Cochrane Library, and hand searches. Two independent 
reviewers screened citations and extracted data. We graded the strength of 
evidence using 4 domains (risk of bias, precision, directness, and consistency) 
and determined the magnitude and direction of effect by calculating the 
relative difference between groups in change from baseline. When possible, we 
conducted meta-analyses using standardized mean differences to obtain aggregate 
estimates of effect size with 95% confidence intervals.

Findings 
After reviewing 18 753 citations, we included 47 trials with 3515 participants. 
Mindfulness meditation programs had moderate evidence of improved anxiety 
(effect size, 0.38 [95% CI, 0.12-0.64] at 8 weeks and 0.22 [0.02-0.43] at 3-6 
months), depression (0.30 [0.00-0.59] at 8 weeks and 0.23 [0.05-0.42] at 3-6 
months), and pain (0.33 [0.03- 0.62]) and low evidence of improved 
stress/distress and mental health–related quality of life. We found low 
evidence of no effect or insufficient evidence of any effect of meditation 
programs on positive mood, attention, substance use, eating habits, sleep, and 
weight. We found no evidence that meditation programs were better than any 
active treatment (ie, drugs, exercise, and other behavioral therapies).

Conclusions and Relevance 
Clinicians should be aware that meditation programs can result in small to 
moderate reductions of multiple negative dimensions of psychological stress. 
Thus, clinicians should be prepared to talk with their patients about the role 
that a meditation program could have in addressing psychological stress. 
Stronger study designs are needed to determine the effects of meditation 
programs in improving the positive dimensions of mental health and 
stress-related behavior.

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