I dug in my old Emails about ACEMANNAN (please note the double N in the spelling, if you use a search engine ACEMANAN won't work), and in effects once I contacted Carrington Labs, and they redirected me to Veterinary Products Laboratories (VPL, http://www.vpl.com), that unfortunately I could not contact at that time because their mail server kept bouncing back my emails. From the info in my possession, injected Acemannan works great with a number of *localized* (i.e. not spread) tumors. Carrington Labs, at that time, did not mention any FDA restriction.
Good luck Paolo