The cat with the ear tumor would be MUCH better off long-term by having the
ear removed than by being on pred long-term. There is a very involved, but
effective total ear abalation surgery that removes the entire ear canal,
including the inner and outer ear, and usually leaves a normal looking ear
flap, but if the tumor involves the flap, you could take that as well. If
it's only on the flap, of course, that's VERY easy to remove.

I have not heard of Pred being used for seizures, but I could be wrong
there.

The extreme nasal discharge you are describing sounds like it began as a
Herpes outbreak, or possibly Calici, and has since turned into a bacterial
nasal infection in some of your cats. I would advise stronger or different
antibiotics if you are not seeing improvement within 1 week of starting your
current antibiotics. Another thing worth trying is testing the mucous for
fungal infection, which often is something that is overlooked unless the
owner specifically requests it be checked for.
Here is a lab service that can test for most URI issues:
http://www.zoologix.com/dogcat/Datasheets/FelineRespiratoryPanel.htm
But, I would consider also doing a fungal test, at least for the most common
nasal fungal infection, Cryptococcosis, as it is a serious issue if left
untreated (the fungus can eat out the bones in the face if left to fester -
it can also lead to some of the other symptoms you mentioned in your other
cats, like blindness, and seizures - it's all around a NASTY thing that
should be seriously considered if antibiotics do not help).
http://www.vin.com/proceedings/Proceedings.plx?CID=WSAVA2003&PID=6653&O=Generic

Phaewryn

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