What I've always heard and done, is you use it *when* they're
asymptomatic, on a regular basis. If you wait till they become ill,
it's too late.
Gloria
On Sep 30, 2009, at 11:11 AM, Esther Jorda wrote:
*Do you use interferon (alfa) with asymptomatic cats or once they
become
ill???*
2009/9/30 Alice Flowers <aliceflow...@sbcglobal.net>
Here are some excerpts from some research on Interferon-I have been
giving
it 2x a day-orally 1 cc to Rosie and Murphy. I had been giving it
onece a
day to the other 4 that passed away. I always give it right before
the
canned food-they both come into the kitchen and pester me, Murphy
bangs the
cabinet door until I get the little syringe filled. Then they sit
and wait
for the little squirt, Rosie will tilt her head sideways-she likes it
squirted on the right side of her mouth, I don't have to force them
to take
it, it's just the routine. I even tasted it, just tastes like saline
solutine-similar to sinus rinse or saline nasal spray. I have not
noticed
any side effects, except maybe lately, combined with the Imulan
treatments
the last 2 weeks-they are playing much more and are awake for
longer periods
and are looking for things to get into. They are making up for
being so sick
the first year.
WHY IS DAILY DOSING BETTER?
Jere Hough
Three Times Weekly Is A Terribly Poor Way to Dose Interferon....
This is a great article and also discusses the development of
longer acting
pegylated interferons to better manage the peak and valley effects
of the
current generation of Interferons:
“PEAKS AND VALLEYS - Because interferon has a half-life in serum of
only
about 7 -10 hours. This means it peaks in the body at about 12
hours and is
then rapidly metabolized and excreted. At 24 hours after injection
it is
barely measurable. By 36 hours it is not detectable with current
measurements. During this peak the is a rapid, dramatic drop in
viral load.
As the levels of interferons quickly drop to negligible levels at
about 24
hours viral loads start rapidly climbing again. By 48 or especially
72 hours
much of the gain in viral reduction has been lost.
In other words, viral loads in the body fluctuate directly and
rapidly
along with levels of interferon in serum, and when plotted on a
graph look
like a sine wave, or a roller coaster. This graph, along with a
description
of this phenomena, can be viewed on many websites and texts on the
subject,
including the http://www.roche-hepc.com/ page. These peaks and
valleys
have been followed for days in human subjects, and are invariably
similar in
those who respond to IFN.
As interferon levels go up viral loads go down immediately. Then as
IFN
levels drop, viral loads increase again rapidly. In the period from
24 to 48
hours viral loads peak to erase most of the gains made. In standard
TIW
dosing the increase in viral loads is even more pronounced during
the 72
hour break once each week.”
1) NEVER give with food. Inteferon breaks down in the stomach with
stomach
acid. Always squirt it directly into the mouth where it is absorbed
in the
mouth and throat lining.
#2) ALWAYS keep refridgerated. It's useless if it hits room
temperature.
Keep unused dilutions frozen until needed. It's unknown how long
Interferon
stays effective in the fridge. Keep unused dilutions frozen until
needed.
#3) It's USELESS to do on/off dosing. It MUST be given every 24
hours to
maintain consistent levels in the bloodstream. (See excerpts below
regarding
peaks and valleys). It must be kept in the blood at all times. On/Off
protocols are worthless because it progresses forward in times of no
intervention.
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--
Esther
= ^..^ =
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