So far, Annie has had no problems and I hope it stays that way. keeping all dealinhg with this in my prayers.
---- Amani Oakley <aoak...@oakleylegal.com> wrote: > Randy > > I really don’t know. I have only had experience with the pills which I found > very effective. As a compromise option, I would take if that is the only way > the vet will agree to proceed. > > Amani > > From: Felvtalk [mailto:felvtalk-boun...@felineleukemia.org] On Behalf Of > Randy Henke > Sent: December-19-16 9:46 AM > To: felvtalk@felineleukemia.org > Subject: Re: [Felvtalk] FW: Questioning FELV diagnosis > > Hi Amani, > I have a call in to our vet now about the Winstrol and Doxycycline. I've read > that there is also the option of getting a weekly shot of Winstrol as opposed > to the pills. If our vet balks at prescribing the pills but would be willing > to give her the shot would it still work as well? > > On Fri, Dec 16, 2016 at 7:12 PM, Amani Oakley > <aoak...@oakleylegal.com<mailto:aoak...@oakleylegal.com>> wrote: > Wishing you luck. > > Amani > > From: Felvtalk > [mailto:felvtalk-boun...@felineleukemia.org<mailto:felvtalk-boun...@felineleukemia.org>] > On Behalf Of Randy Henke > Sent: December-16-16 8:12 PM > > To: felvtalk@felineleukemia.org<mailto:felvtalk@felineleukemia.org> > Subject: Re: [Felvtalk] FW: Questioning FELV diagnosis > > Thank you, Amani! I'll see what I can do to convince the vet on Monday. > > On Fri, Dec 16, 2016 at 6:54 PM, Amani Oakley > <aoak...@oakleylegal.com<mailto:aoak...@oakleylegal.com>> wrote: > 1 mg 2 times a day. > > Amani > > From: Felvtalk > [mailto:felvtalk-boun...@felineleukemia.org<mailto:felvtalk-boun...@felineleukemia.org>] > On Behalf Of Randy Henke > Sent: December-16-16 7:52 PM > To: felvtalk@felineleukemia.org<mailto:felvtalk@felineleukemia.org> > Subject: Re: [Felvtalk] FW: Questioning FELV diagnosis > > That is information that is definitely useful to me! Thanks so much! Do you > know what dosage of Winstrol I should ask for for a 6.8 pound cat? I want to > have as much info as possible when I talk to my vet on Monday. > > On Fri, Dec 16, 2016 at 4:25 PM, Amani Oakley > <aoak...@oakleylegal.com<mailto:aoak...@oakleylegal.com>> wrote: > No Randy, Winstrol is an anabolic steroid (unlike prednisone which is a > corticosteroid) so it does not have a dampening effect on the immune system. > What you need right now is something to stimulate red cell production. If > your cat has FELV, then the problem is that the progenitor cells in the bone > marrow will have been infiltrated/killed by the virus and thus, the red cell > production is down. Red cells have a life span of 120 days in circulation, so > once that is over and they die, then they must be replenished by a steady > supply of new cells from the bone marrow. > > The only thing I have found that will do that is Winstrol. However, I use it > in a cocktail with Doxycycline which has been found to retard the > reproduction of viral RNA, and prednisone. This is the only combination of > drugs that worked when my cat was in FELV crisis and had a haematocrit result > of 5 (with the reference range being something like 25 to 35, off the top of > my head). I had tried LTCI and interferon and even though I tested his blood > weekly, I saw no change/improvement at all in his red cell count, > haematocrit, hemoglobin, platelets, etc. It was only when I stumbled upon the > use of Winstrol (he was already on prednisone and Doxy, but they don’t work > without the Winstrol), that I saw a steady and sustained improvement in his > haematology numbers. > > The scandal, Randy, is that Winstrol is one of the steroids often implicated > in athletic doping scandals, so vets seem to be gun shy about prescribing it. > Also, some years ago, a very poorly conducted experiment was published where > cats where given 10 times the recommended dose of Winstrol as a “loading > dose” and developed liver problems. So between these two driving forces, you > have a lot of uneducated vets who will either think you are “unethical” for > asking for the Winstrol, or believe it is a harmful drug thanks to the stupid > scientific study that was published. Plus, even where they are willing to > prescribe it (like in Sherri’s case) they don’t recognize the need to couple > it with the Doxycycline, and thus, you do get a weak boost of the red cells, > etc., but the virus is reproducing rampantly, so in the end, the virus wins. > (Then, of course, not recognizing the need for the Doxy, those same vets will > view the use of Winstrol as a failure and not likely use it again.) > > Other medications that might increase red cell production are erythropoietin > and related medications, but erythropoietin does not encourage bone marrow > growth and development as Winstrol does. Thus, if the progenitor cells in the > bone marrow, which produce red cells, white cells and platelets, have been > killed by the virus (or converted to infected cells, spewing out more virus) > then the erythropoietin will not be effective because it simply encourages > those progenitor cells to produce more red cells. However, because they can’t > and thus cannot respond to the stimulation by erythropoietin. (If your cat > doesn’t have FELV, and has anemia because of some other cause, then the > erythropoietin might work.) > > Winstrol stimulates bone production (experiments have used it effectively in > older adults for osteoporosis), and I don’t anything else which fits the bill. > > Cats with FELV often also have lymphocytes lining the intestinal walls, or > other problems with moving food through the intestines. My cat did, and that > resulted in (a) loss of appetite (b) vomiting and (c) slow bowel movements. I > therefore found it necessary to add a ¼ tablet of metoclompromine (Reglen) > before meal times twice a day. Worked like a charm. > > This cocktail then brought my baby back from the brink of certain death. I > had given him blood transfusions with his anemia, but that is only a > short-term solution and he wasn’t producing any red cells (reticulocyte count > was basically zero – this is a measure of new red cell production and should > be increased in cases of anemia to demonstrate that the body is producing red > cells to compensate for the reduced red cell count). He had had a reaction > with his last blood transfusion, and so no more transfusions were possible > since the next one would kill him, and I was all out of options as I watched > his haematocrit level drop lower and lower, week by week. It had dropped to > 10 when I “discovered” an old bottle of Winstrol in my drawer. > > Whew. Guess how many times I have given this speech?? > > Amani > > From: Felvtalk [mailto:felvtalk-boun...@felineleukemia.org] On Behalf Of > Randy Henke > Sent: December-16-16 9:15 AM > To: felvtalk@felineleukemia.org<mailto:felvtalk@felineleukemia.org> > Subject: Re: [Felvtalk] Questioning FELV diagnosis > > It's interesting that our vet was very hesitant about even prescribing > Prednisone because he is afraid it will suppress her immunity to secondary > infections. I know that is a risk. Would adding Winstrol suppress her immune > system even further? I'm very confused about how to proceed. > > On Thu, Dec 15, 2016 at 10:23 PM, Ardy Robertson > <ar...@centurytel.net<mailto:ar...@centurytel.net>> wrote: > If I can chime in on Winstrol, it did wonders on my Tigger to get his > bloodwork up. I only wish I had started it sooner, along with the > prednisolone and doxycycline. > Best of luck! > Ardy > > > _______________________________________________ > Felvtalk mailing list > Felvtalk@felineleukemia.org<mailto:Felvtalk@felineleukemia.org> > http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org > > > _______________________________________________ > Felvtalk mailing list > Felvtalk@felineleukemia.org<mailto:Felvtalk@felineleukemia.org> > http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org > > > _______________________________________________ > Felvtalk mailing list > Felvtalk@felineleukemia.org<mailto:Felvtalk@felineleukemia.org> > http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org > _______________________________________________ Felvtalk mailing list Felvtalk@felineleukemia.org http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org
