Hi,

I found the reference to D. Van Essen's paper:

Van Essen, D and Drury, H (1997) "Structural and functional analyses of human cerebral cortex using a surface-based atlas" J Neurosci 17 (18):7079-7102

and the folding index is defined (from that paper) as "the integral of the product of the maximum principal curvature and the difference between maximum and minimum curvature, divided by 4*pi", ie,

FI= (1/4pi) \int \int |kmax|(|kmax|-|kmin|) dA

is this what freesurfer is using?

thanks,

roberto

On 8 Feb 2006, at 16:39, Bruce Fischl wrote:

the Gaussian and mean curvature are differential geometric measures and you can find them in any standard textbook (e.g. do Carmo). The folding indices come from one of David Van Essen's papers - sorry, I don't have the reference offhand, but it shouldn't be too hard to find.

Bruce

On Wed, 8 Feb 2006, Goradia, Dhruman D wrote:

Hi,

The output of function "mris_anatomical_stats" contains the following
measurements: integrated rectified mean curvature, integrated rectified
Gaussian curvature, folding index and intrinsic curvature index. Can
someone please give me a brief explanation of what these measurements
are or suggest some reading material.

-Dhruman



Dhruman D. Goradia (M.S.)

Research Specialist.

Western Psychiatric Institute and Clinic.

3811 O'Hara St. Suite 431

Pittsburgh, PA 15213

Phone: 412-586-9017




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