Ryan,

Be sure to have a look at ribbon.mgz, as that is a volume file created
using the white and pial surfaces (from mris_volmask), and would be the
most accurate of the volume files in regards to gm segmentation.

Nick

On Fri, 2009-03-27 at 10:53 -0400, Ryan Scotton wrote:
> Hi Bruce,
> 
> I've uploaded an example of a case with fairly accurate white and pial
> boundries when viewed on top of the wm.mgz volume, and GM areas that
> are not segmented and others
> which have a very fuzzy/noisy boundary within the aparc+aseg.mgz
> volume.
> 
> Also, I'm not sure what email client you're using, but since my first
> email failed to come through, I ended up forwarding it and sending it
> to you again yesterday, which is the one you received.  I noticed that
> in gmail, it will hide the quoted text, which contained my best
> description of the problems we're seeing and my FS version (3.0.4).
> You may have already read it, I'm not sure, but just in case, it's
> inline with this email.
> 
> The file I uploaded is named 5008-003-02_scotton.tar.gz
> 
> Thanks so much for your help,
> 
> Ryan
> 
> On Thu, Mar 26, 2009 at 5:36 PM, Bruce Fischl
> <fis...@nmr.mgh.harvard.edu> wrote:
>         Hi Ryan,
>         
>         I still don't quite understand what I'm looking at. Maybe you
>         can put a problem subject somewhere we can get to it?
>         
>         cheers,
>         Bruce
>         
>         
>         
>         On Thu, 26 Mar 2009, Ryan Scotton wrote:
>         
>                 For whatever reason, my email from this morning
>                 doesn't seem to have gone
>                 through.  Hopefully it will work this time...
>                 
>                 Ryan
>                 
>                 ---------- Forwarded message ----------
>                 From: Ryan Scotton <ryan.scot...@gmail.com>
>                 Date: Thu, Mar 26, 2009 at 10:25 AM
>                 Subject: Re: [Freesurfer] Incorrect correspondence in
>                 the aparc+aseg.mgz
>                 volume?
>                 To: Bruce Fischl <fis...@nmr.mgh.harvard.edu>
>                 Cc: freesurfer@nmr.mgh.harvard.edu
>                 
>                 
>                 Hello again Bruce,
>                 
>                 We used FreeSurfer version 3.0.4, so an older
>                 version.  I've attached 9
>                 screen shots...the first 6 are from the same subject,
>                 and the last three
>                 (the jpgs with _2 at the end of them) were included
>                 just to give a better
>                 idea of the problems we're seeing in the aparc
>                 +aseg.mgz volume, despite good
>                 surfaces in the wm.mgz volume (screenshots of the
>                 wm.mgz were not included
>                 for the 2nd volume...they are equally accurate as the
>                 first case I sent).
>                 You'll notice that there are many GM areas that are
>                 not segmented and others
>                 which have a very fuzzy/noisy boundary.  Do you think
>                 that there is some
>                 kind of error occuring in the spherical registration
>                 step?  If so, how can
>                 one QC this step?  Or is it some other issue entirely?
>                 
>                 Thanks for your help,
>                 
>                 Ryan
>                 
>                 
>                 
>                 On Tue, Mar 24, 2009 at 5:01 PM, Bruce Fischl
>                 <fis...@nmr.mgh.harvard.edu>wrote:
>                 
>                         Hi Ryan,
>                         
>                         what version are you using? And when you say
>                         "bad" what exactly do you
>                         mean? Can you send some snapshots? If you're
>                         doing a thickness study the
>                         aparc+aseg is irrelevant - just the white and
>                         pial surfaces matter (and the
>                         spherical registration of course)
>                         
>                         
>                         cheers
>                         Bruce
>                         
>                         On Tue, 24 Mar 2009, Ryan Scotton wrote:
>                         
>                          Hi FreeSurfers,
>                                 
>                                 After a months of QC'ing FreeSurfer
>                                 results, my team and I are now working
>                                 toward end stage analysis of our
>                                 cortical thickness data.  All along,
>                                 we
>                                 have been aiming to make improvements
>                                 in the wm.mgz volume so that we can
>                                 assure that the white matter and gray
>                                 matter surfaces are as accurate as
>                                 possible.  This was under the
>                                 assumption that if the white matter
>                                 and gray
>                                 matter surfaces are accurate, then the
>                                 voxel-wise representation of the
>                                 white and gray matter in the aparc
>                                 +aseg.mgz file would be accurate.
>                                 However, in almost all of our cases,
>                                 the aparc+aseg.mgz segmentation looks
>                                 very bad.  The bad aparc+aseg.mgz
>                                 representation of what seem to be
>                                 accurate
>                                 white and gray matter segmentations in
>                                 the wm.mgz file is leading us to
>                                 believe that the cortical
>                                 correspondences created after template
>                                 mapping
>                                 are
>                                 wrong.
>                                 
>                                 Does anyone else have an explanation
>                                 for such a discrepancy?  Is this a
>                                 common problem and if so, is there any
>                                 way to remedy this situation?
>                                 
>                                 Thanks,
>                                 
>                                 Ryan
>                                 
>                                 
>                 
> 
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