I doubt it's going to make that much difference, but if I had to choose, 
I'd choose the formula that you have below (note the the areas should be 
added together in the denominator).

doug

Liang, Kelvin wrote:
> Dear FreeSurfer Experts,
>
> I'd like to merge my cortical thickness measures across left and right 
> hemispheres.  Simple averaging of the ?h.thickness values would probably be 
> the most straightforward method, but would it be more accurate to use a 
> surface-area weighted average?
>
> i.e. entorhinal_combined = (lh_entorhinal_thickness * lh_entorhinal_area + 
> rh_entorhinal_thickness * rh_entorhinal_area) / (lh_entorhinal_area * 
> rh_entorhinal_area)
>
> Alternatively, the average could be weighted by the number of vertices 
> (discussed in an old FreeSurfer mailing thread, but never quite concluded).  
> Please let me know what you think.
>
> Thank you,
> Kelvin Liang
>
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