Hi Doug,



By "more exactly location" I want to say that I would like to have the MNI 
coordinates and also the annotation location or the nearst cortical label (for 
example precentral or lateraloccipital, etc).
Also,after I ran the mri_segstatsI don't have the MNI coordinates.

Thanks for helping.
Antonella


From: Douglas N Greve <gr...@nmr.mgh.harvard.edu>
To: Antonella Kis <ator...@yahoo.com>; freesurfer 
<freesurfer@nmr.mgh.harvard.edu> 
Sent: Tuesday, February 14, 2012 1:18 PM
Subject: Re: [Freesurfer] Clusters locations
 


Antonella Kis wrote:
> Hi Doug,
>
> 1) I would like to report the MNI coordinates and also a more exactly 
> region I mean if possible tto find exactly where in the 
> Left-Cerebral-White-Matter and Right-Cerebral-White-Matter my cluster 
> is located.
What do you me by "exactly where"? The nearest cortical label? The fiber 
bundle?
>
> 2)Can you please tell me if for the mean diffusivity I should use the 
> simulation with the perm (as I use for the FA due to the fact that is 
> not so Gaussian) option  or it is OK to use the grf option.
I think you can use GRF for this as it corresponds to a normal contrast 
in a GLM. Note that the permutation is the stronger (but more 
conservative) test.
>
>
> 3) Can you please explain what exactly means for my clusters if I hit 
> the positive sign under DISPLAY in Qdec? I mean if I compare the 
>
 cortical thickness between two classes: controls vs. Patients and
> I am not interested in the sex or age differences just differences 
> between the two classes will positive mean clusters where cortical 
> thickness graeter in Class 1 than Class2 (Class1>Class2)?
>
> I have C = +1 -1 and my Class 1 = controls while Class2 = PAtients.
Positive is Controls > Patients

doug
>
>
> THANKS YOU.
> Antonella
> ------------------------------------------------------------------------
> *From:* Douglas Greve <gr...@nmr.mgh.harvard.edu>
> *To:* Antonella Kis <ator...@yahoo.com>; free surfer 
> <freesurfer@nmr.mgh.harvard.edu>
> *Sent:* Tuesday, February 14, 2012 9:59 AM
> *Subject:* Re: [Freesurfer] Clusters locations
>
> Hi Antonella, what level of detail do you want? I think that most 
> people are reporting MNI coordinates.
> doug
>
> On 2/13/12 2:44 PM, Antonella Kis wrote:
>> Hi Doug,
>>
>> I will be very grateful if you give me some directions regarding how 
>> I can get my clusters location ( my output is too general telling me 
>> just Left-Cerebral-White-Matter and Right-Cerebral-White-Matter) and 
>> the coordinates (MNI) when I run the:
>>
>> mri_volcluster --in GroupAnalysis_pos.glmdir/contrast/sig.mgh --mask 
>> GroupAnalysis_pos.glmdir/mask.mgh --no-fixmni --cwsig 
>>
 GroupAnalysis_pos.glmdir/contrast/permcsd.sig.cluster.mgh --sum 
>>
 GroupAnalysis_pos.glmdir/contrast/permcsd.sig.cluster.summary --ocn 
>> GroupAnalysis_pos.glmdir/contrast/permcsd.sig.ocn.mgh --cwpvalthresh 
>> .09 --seg cvs_avg35 aseg.mgz --csdpdf 
>> GroupAnalysis_pos.glmdir/contrast/permcsd.pdf.dat --csd 
>> GroupAnalysis_pos.glmdir/csd/permcsd.j001-contrast.csd --vwsig 
>> GroupAnalysis_pos.glmdir/contrast/permcsd.sig.voxel.mgh
>>
>> and
>>
>>
>> mri_segstats --seg  permcsd.sig.ocn.mgh  --exclude 0 --i 
>> /media/2Tra/Antonella_2011/DTI_FS/GLM_CVS/GroupAnalysis-FA-MASKED.ANAT+CVS-to-avg35.nii.gz
>>  
>> --avgwf fa.avg.dat --sum permcsd.sig.cluster.summary
>>
>>
>> Thank you.
>> Antonella
>
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-- 
Douglas N. Greve,
 Ph.D.
MGH-NMR Center
gr...@nmr.mgh.harvard.edu
Phone Number: 617-724-2358 
Fax: 617-726-7422

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