Our reply to that is here http://bjp.rcpsych.org/content/196/5/414.2.long
which reminded me of other papers that have also used a global thickness measure to covary for mean cortical thickness and thereby "address whether any regional thickness differences were in excess of global cortical thickness differences between groups" -- see references [1,4] in our Reply. cheers, -MH > Hi Michael and others, > > maybe it's this one: > > http://bjp.rcpsych.org/content/196/5/414.1.long > > best, > -joost > > > On Fri, Mar 23, 2012 at 2:15 AM, Michael Harms > <mha...@conte.wustl.edu>wrote: > >> >> Hi Jeff, >> I personally like the idea of using average thickness as a covariate to >> control for a reduction in "whole brain" thickness, and have used that >> approach in a paper. If the Abstract that you mentioned indicated that >> this is flawed, I'd be curious to know what the reason was... >> >> cheers, >> -MH >> >> On Thu, 2012-03-22 at 21:00 -0400, Bruce Fischl wrote: >> > Hi Jeff >> > >> > yes, I think this is still our recommendation for thickness, although >> > perhaps David Salat can verify. As far as surface area, you might get >> > Anderson Winkler to send you a preprint of his newly accepted paper on >> > surface area comparisons and how to do them properly. I would have >> said >> > normalize by the 2/3 root of ICV (maybe David can comment on this as >> well) >> > >> > cheers >> > Bruce >> > >> > >> > On Thu, 22 Mar 2012, Jeff Sadino wrote: >> > >> > > Hello, >> > > For cortical thickness normalizations, Bruce said not to normalize >> based on a HBM >> > > abstract >> > > ( >> http://www.mail-archive.com/freesurfer@nmr.mgh.harvard.edu/msg06646.html). >> Is >> > > this still the consensus? >> > > >> > > For cortical volume, it is pretty standard to normalize to eTIV. >> > > >> > > For cortical surface area (jacobian), I couldn't find any >> information >> on the wiki. >> > > Does anyone have any recommendations? >> > > >> > > Thank you, >> > > Jeff >> > > >> > > >> > _______________________________________________ Freesurfer mailing >> list >> Freesurfer@nmr.mgh.harvard.edu >> https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer The >> information in this e-mail is intended only for the person to whom it is >> addressed. If you believe this e-mail was sent to you in error and the >> e-mail contains patient information, please contact the Partners >> Compliance >> HelpLine at http://www.partners.org/complianceline . If the e-mail was >> sent to you in error but does not contain patient information, please >> contact the sender and properly dispose of the e-mail. >> >> _______________________________________________ >> Freesurfer mailing list >> Freesurfer@nmr.mgh.harvard.edu >> https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer >> > _______________________________________________ Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
