Dear Freesurfers:
 
We have a large group of subjects (for which we have two time-points)
that were run  through the
recon-all stream using 5.0.  We
have done no manual editing yet.
 
We would like to do a longitudinal analysis of these
subjects using 5.1 by comparing both time-points for each subject.  Is that a 
possibility using 5.1? 
 
Also, at what point should I correct for topographical
defects, or make edits to the white matter or brain mask volume?
Should I edit both time-points separately first and then initiate
the longitudinal analysis? If so, could I do the manual editing using 5.1?

thank you very much for your help,
cheers,
cat
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