Hi Bruce,

First, let me add that if I run the mri_segstats without the --pv flag, the
two will have identical volumes. This indicates to me that we captured all
the voxels into the new label.

Joshua

-
Joshua Lee
Graduate Student
Center for Mind and Brain &
Department of Psychology
University of California, Davis
530.747.3805


On Wed, May 16, 2012 at 1:38 PM, Bruce Fischl <fis...@nmr.mgh.harvard.edu>wrote:

> Hi Joshua
>
> probabilities are computed internally, but not stored nor used in volume
> calcualtions. Are you actually doing a 3D fill? I don't think the
> hippocampus label is guaranteed to be connected. Can you try instead
> replacing every voxel in matlab with the hippocampus index to your new one?
> That I think should give you the same results.
>
> cheers
> Bruce
>
>
>
> On Wed, 16 May 2012, Joshua Lee wrote:
>
>  Suppose I were to open a subject aseg.mgz in tkmedit, and use the 3D fill
>> tool to relabel the entire left hippocampus segmentation to
>> 'MyNewImaginaryLabel'. If I then re-run the aseg stats, should the left
>> hippocampus volume from the original aseg.stats be identical to the volume
>> of MyImaginaryLabel in the newly generated aseg.stats?
>>
>>  Every voxel from the prior label is now assigned to the new label; yet, I
>> am getting different results (by about 100 voxels in the ones I've tried).
>>
>> The command Im using to recalculate:
>> mri_segstats --seg
>> /usr/local/freesurfer/**subjects/s02/new_MRI/new/aseg.**auto.mgz --sum
>> /usr/local/freesurfer/**subjects/s02/stats/**NEWmethod1aseg_Hipp.stats
>> --pv
>> /usr/local/freesurfer/**subjects/s02/mri/norm.mgz --excludeid 0
>> --brain-vol-from-seg --brainmask
>> /usr/local/freesurfer/**subjects/s02/mri/brainmask.mgz --in
>> /usr/local/freesurfer/**subjects/s02/mri/norm.mgz --in-intensity-name
>> norm
>> --in-intensity-units MR --etiv --surf-wm-vol --ctab
>> /usr/local/freesurfer/**8regions.txt --subject s02;
>>
>> Now if I were to relabel 'MyNewImaginaryLabel' to 'AthirdLabel', and again
>> changing every voxel in 'MyNewImaginaryLabel' to the new label, the
>> computed
>> volumes do not change. This led me to suspect that aseg.mgz contains
>> probability estimates at each voxel that are then subsequently overwritten
>> by my tkmedits. However, per a previous conversation from a year ago or so
>> with Bruce and also the relevant Freesurfer documentation this does not
>> seem
>> to be the case. Partial volume information is not contained within the
>> aseg.mgz (right!?), but is computed by mri_segstats by comparing border
>> voxels with intensities in the norm.mgz. So I am at a loss on why these
>> should be different.
>>
>> This has been replicated in version 4.5 and 5.1
>> -
>> Joshua Lee
>> Graduate Student
>> Center for Mind and Brain &
>> Department of Psychology
>> University of California, Davis
>> 530.747.3805
>>
>>
>>
>
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