Hi Joshua, when you add --fwhm 15 to the command line you are instructing mri_glmfit to smooth by 15mm. Is this what you want? Or is the data already smoothed?
doug


On 6/3/13 12:26 AM, Joshua deSouza wrote:
Hi Doug,

The command line is mri_glmfit --y lh.t.15.mgh --fsgd t.txt dods --C t1.txt --surface fsaverage lh --cortex --fwhm 15 --glmdir lh.t.15.glmdir

I am doing a whole hemisphere analysis and am measuring cortical thickness. I do not have my own mask but I have doubts about the mask that has been produced because from previous studies, there has been significant thinning in the area around the hippocampus and parts of it are being left out in the mask, such as the para-hippocampal region.

Regards

Joshua

On Mon, Jun 3, 2013 at 10:54 AM, Douglas Greve <gr...@nmr.mgh.harvard.edu <mailto:gr...@nmr.mgh.harvard.edu>> wrote:


    The residual FWHM is measured from the data itself. You apply a
    certain amount of smoothing, but there is already some smoothness
    to the data, so the final fwhm is a combination of what is already
    there and what you apply. A fwhm of 47 is huge and may indicate
    that something is wrong. What is the input? cortical thickness?
    Are you using your own mask or is this a whole hemisphere analysis?

    doug






    On 6/2/13 10:29 PM, Joshua deSouza wrote:
    Hello Doug,

    Thank you for your quick replies to my queries. Really appreciate
    it.

    I have found the files containing the cortical thickness values.
    Thank you. I assume that the order in which they follow are based
    on the fsgd file and the cluster annotation numbers.

    I was just slightly confused about the residual fwhm. I have
    already done a smoothing of 15 on the file and have recieved a
    residual value of 47, which I assume is extremely large. Since
    I'm finding out values for the entire cortex I cannot do a
    glmfit-sim as there are no fwhm cache values of 47. Could you
    please tell me what the residual values mean?  What do you
    recommend I do? Is there anything I can read up on to find out
    more about this? (Please pardon my questions if they seem a
    little trivial)

    Thank you

    Joshua

    On Sun, Jun 2, 2013 at 11:33 PM, Douglas Greve
    <gr...@nmr.mgh.harvard.edu <mailto:gr...@nmr.mgh.harvard.edu>> wrote:


        This file is always created by mri_glmfit-sim. It might be
        named something different depending on your parameters
        (should always end in y.ocn.dat)
        doug


        On 6/2/13 3:57 AM, Joshua deSouza wrote:
        Hi Doug,

        This file that your saying, will be created after glmfit-sim
        is done using the cache function and a threshold of 1.3 and
        absolute ,with y being the fsgd file? Am I understanding
        this correctly?

        Thank you

        Joshua

        On Sat, Jun 1, 2013 at 12:14 AM, Douglas N Greve
        <gr...@nmr.mgh.harvard.edu
        <mailto:gr...@nmr.mgh.harvard.edu>> wrote:

            There should be a file called something like
            cache.th13.abs.y.ocn.dat.
            This will have a column for each cluster and a row for
            each subject. The
            value in the row will be the input for each subject.
            doug

            On 05/30/2013 11:21 PM, Joshua deSouza wrote:
            > Hello everyone,
            >
            > Please pardon my rather simple question
            >
            > I have done a GLM fit anlysis and have obtained a file
            sig.mgh alonf
            > with a few others after the analysis.As I know, I do
            not have to
            > create ROIs in order to do this. I also understand
            that doing a
            > multiple comparison analysis just compares the regions
            of importance
            > and evaluates them giving the most resilient cluster
            depending on the
            > threshold. So, this does not give a thickness
            estimate. I would like
            > to know how do I get the cortical thickness values
            from the results?
            > If so, can I do it after glmfit?
            >
            > And thanks Doug for your help in the other questions
            that I had prior
            > to this!
            >
            > Thank you
            >
            >
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            MGH-NMR Center
            gr...@nmr.mgh.harvard.edu <mailto:gr...@nmr.mgh.harvard.edu>
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