Hi Bruce,

Thanks for the reply. Would 'bbregister' work to register the files to
eachother or would there be a more useful way to do that?

Also I noticed that across many of the subjects there is a slight
difference in the TR, TE, TI, and flip angle values.

For instance, one of the subjects has a TR: 9.39 and another might have a
TR: 9.44. This clearly prevents me from using them to create an atlas. I am
not really sure why these values are slightly off, they should be the same.
Is there anyway to change those values manually? Is it because I am using
the T1.mgz files?

Thank you!

- MP


On Tue, Jul 23, 2013 at 3:15 PM, Bruce Fischl <fis...@nmr.mgh.harvard.edu>wrote:

> Hi Mark
>
> have you tried using  a transform? Usually with more than one subject we
> require that they be registered. I haven't looked at that code in a long
> time, so I am not positive that it would fix this problem, but it might. In
> any case if they aren't registered it won't generate a useful atlas, even
> if it does run to completion
> Bruce
>
>
> On Tue, 23 Jul 2013, Mark Plantz wrote:
>
>  Hello freesurfers,
>>     I recently ran into a problem with mri_ca_train, a function that
>> creates
>> a .gca atlas from a manually segmented volume and input volume(s).
>>
>>   My command line is:
>>
>> mri_ca_train -T1 T1.mgz CMH-11460 CMH-11461 ~/Desktop/atlas.gca
>>
>> The results:
>>
>> processing subject CMH-11461, 1 of 1...
>>    reading input 0:
>> /Volumes/Wong_Lab/LabMRIData/**FreeSurfer/CMH-11461/mri/norm.**mgz
>> filling holes in the GCA...
>> 404261 classifiers: 1.5 per node, 7.59 in brain (0 holes filled)
>> computing covariances for subject CMH-11461, 1 of 1...
>> average std = 6.1   using min determinant for regularization = 3.7
>> 298584 singular and 4268 ill-conditioned covariance matrices regularized
>> writing trained GCA to /Users/IngvalsonLab/Desktop/**atlas1.gca...
>> classifier array training took 0 minutes and 27 seconds.
>> dhcp-165-124-23-230:LabMRIData IngvalsonLab$
>> dhcp-165-124-23-230:LabMRIData IngvalsonLab$
>> dhcp-165-124-23-230:LabMRIData IngvalsonLab$ mri_ca_train -T1 T1.mgz
>> CMH-11460 CMH-11461 ~/Desktop/atlas1.gca
>> reading T1 data from subject's mri/T1.mgz directory
>> training on 2 subject and writing results to
>> /Users/IngvalsonLab/Desktop/**atlas1.gca
>> ****************************************************************
>> ***************
>> processing subject CMH-11460, 1 of 2...
>>    reading input 0:
>> /Volumes/Wong_Lab/LabMRIData/**FreeSurfer/CMH-11460/mri/T1.**mgz
>> ****************************************************************
>> ***************
>> processing subject CMH-11461, 2 of 2...
>>    reading input 0:
>> /Volumes/Wong_Lab/LabMRIData/**FreeSurfer/CMH-11461/mri/T1.**mgz
>> filling holes in the GCA...
>> 468392 classifiers: 1.8 per node, 10.41 in brain (0 holes filled)
>> computing covariances for subject CMH-11460, 1 of 2...
>> GCAupdateNodeCovariance(17, 35, 28, 4): could not find label
>> dhcp-165-124-23-230:LabMRIData IngvalsonLab$
>>
>>
>>    According to the fswiki, the same bug was eliminated in the 2009
>> version.
>> For some odd reason, this command works with one subject, but not with
>> multiple subjects.
>>
>> Any ideas?
>>
>> Thanks in advance,
>>
>> MP
>>
>>
>>
>
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