Hi Octavian,

If you have an OK aseg volume, you could try to fit a 
surface over it using mris_make_surfaces with the -cover_seg flag.

Lilla


On Tue, 25 Nov 2014, Bruce Fischl wrote:

>
>
> ---------- Forwarded message ----------
> Date: Tue, 25 Nov 2014 08:05:55 -0600
> From: Octavian Lie <octavian....@gmail.com>
> Reply-To: Freesurfer support list <freesurfer@nmr.mgh.harvard.edu>
> To: Freesurfer support list <freesurfer@nmr.mgh.harvard.edu>
> Subject: Re: [Freesurfer] Fwd: Eccentric lesions
>
> It looks like there is only gray matter (int 42), similar to cortical ribbon
> gray, no white matter in that gyrus in aseg, both in the original recon, and
> after painting gyral centers in brainmask.
> Octavian
>
> On Tue, Nov 25, 2014 at 7:51 AM, Octavian Lie <octavian....@gmail.com>
> wrote:
>       Dear Bruce,
>
> I am not sure how an ok aseg.mgz would look like for a lesion like
> that, but it looks like it includes one larger gyrus excluded by the
> pia, see attached, I would be happy to retrieve that one as it is the
> bulkiest of all the ones left out.
> Thank you,
>
> Octavian
>
> On Tue, Nov 25, 2014 at 7:38 AM, Bruce Fischl
> <fis...@nmr.mgh.harvard.edu> wrote:
>       Hi Octavian
>
>       I wouldn't use control points since it really isn't
>       healthy wm. The only
>       thing you can do is edit the wm.mgz and possibly also the
>       brainmask, but
>       it's so abnormal looking you may not be able to get
>       accurate surfaces.
>       How does the aseg look? If it is ok there may be one other
>       option.
>
>       cheers
>       Bruce
>
>
>      On Tue, 25 Nov 2014, Octavian Lie wrote:
>
>      >  Dear All,
>      >  any suggestion about this type of problem? I tried
>       control points through
>      >  the middle/axis of the atrophic gyri (intensity 30-90 in
>       T1 or brainmask),
>      >  wm.mgz edits through the same (adding from brainmask by
>       cloning those
>      >  voxels; painting 110; or 255 brush), and modifying
>       brainmask directly by
>      >  painting 110 internsity voxels through the same (gyri
>       interiors, where wm is
>      >  supposed to be). Did not work, the atrophic gyri
>       continue to remain outside
>      >  the pia. Again, this is an example of an eccentric
>       lesion with gyral
>      >  atrophy, without interruption in the gray matter ribbon
>       but very faint wm
>      >  signal through the base of the affected gyri.
>      >  Thanks,
>      >  Octavian
>      >
>      >
>      >
>      >  ---------- Forwarded message ----------
>      >  From: Octavian Lie <octavian....@gmail.com>
>      >  Date: Tue, Nov 18, 2014 at 10:50 AM
>      >  Subject: Eccentric lesions
>      >  To: "freesurfer@nmr.mgh.harvard.edu"
>       <freesurfer@nmr.mgh.harvard.edu>
>      >
>      >
>      >  Dear All,
>      >
>      >  I am interested at getting as good pial/cortical
>       reconstructions as possible
>      >  on a series of epilepsy pt scans, some showing eccentric
>       (cortical) lesions
>      >  (focal encephalomalacias, infarcts, or after focal
>       resections). One
>      >  particularly difficult lesion type to get an accurate
>       cortical surface is
>      >  where there are prongs of grey matter bulging out (like
>       a bag of worms),
>      >  (mostly) without visible wm, see attached picture. These
>       prongs are
>      >  maintained in the brainmask.mgz and
>       brain.finalsurfs.mgz, but not included
>      >  in the pia with the default recon. Lesion voxel
>       intensities vary from 30-90.
>      >  I tried cp, wm edits (using brainmask or T1 as
>       referece), both, did not
>      >  matter, it did not work.
>      >
>      >  Since I am not intested in wm/subcortical segmentation
>       but just in a good
>      >  pia, I was wondering if I 'create' thin wm tracts
>       through the center of
>      >  these gm prongs to help pial segmentation. If this is a
>       valid option, should
>      >  I create those in brainmask, brain.finalsurfs or wm.mgz,
>       and should I use
>      >  110 or 255 for the brush?
>      >  Any other suggestions are appreciated. Nevertheless, I
>       know there is a lot
>      >  of tweaking of each lesion, and I try for more of a
>       global approach to these
>      >  kinds of lesions.
>      >
>      >  Thank you,
>      >
>      >  Octavian.
>      >
>      >
>      > 
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