yes, just note that they are somewhat different hypothoses that you are testing as noted by Mike in the past. If you use average surface area/thickness you are testing the hypothesis that part of the brain is not changing/different relative to the average. If you control for TIV (or the 2/3 root of it I guess for surface area) you are looking for any change while removing head size as a nuisance variable. I think Mike's is probably the more interesting approach, but they are somewhat distinct.
cheers Bruce On Mon, 4 Jul 2016, Arkadiy Maksimovskiy wrote: > Hi Clara, > Yes- my apologies. I misunderstood your initial analyses description. Sounds > right to me as well. > > - Arkadiy > > _______________________________________________ Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in error and the e-mail contains patient information, please contact the Partners Compliance HelpLine at http://www.partners.org/complianceline . If the e-mail was sent to you in error but does not contain patient information, please contact the sender and properly dispose of the e-mail.