Hello, We have been trying to analyze some longitudinal structural data using the FreeSurfer Mixed Effects Model toolbox and have been running into some issues.
We have 2-3 timepoints per individual imaged across adolescence and 3 groups of interest. We set up a design matrix to examine potential quadratic effects of age by group including factors for: 1. Intercept 2. time 3. time ^2 4. Group 1 vs. others 5. Group 1 x time 6. Group 1 x time ^2 7. Group 2 vs. others 8. Group 2 x time 9. Group 2 x time ^2 10. age at baseline 11. sex We started a model to examine thickness, testing out the first model below [lhTh0,lhRe] = lme_mass_fit_EMinit(X,[1 2 3],Y,ni,lhcortex); Then, we have been getting stuck at [lhRgs,lhRgMeans] = lme_mass_RgGrow(lhsphere,lhRe,lhTh0,lhcortex,2,95); This starts the segmentation into homogeneous region but seems to get stuck after displaying "Computing seeds..." Is there a way to diagnose or fix this problem? Any thoughts would be great, thanks!
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