So, it looks ok in the volume (using tkmedit) but not on the surface (using tksurfer)? Something is definitely weird. The only thing I can think of is that the surface is not the surface of the subject you think it is. What is your tksurfer command line? What is the subject name in the contents of the registration file?

On 7/3/17 11:39 AM, Taylor, Johnmark wrote:
Hello,

I am running into an odd issue. In particular, I have run a GLM analysis in _volume_ space, and I am visualizing the results both on the surface using tksurfer, and on the volume using tkmedit. In both cases, I am using the register.dof6.dat file to do the registration. Oddly, when I visualize the results on the _surface_, the activation patch falls on the medial surface of the hemisphere, in the _precuneus_, whereas when I visualize the results on the _volume_, the patch is in the _intraparietal sulcus_ (which is where we expect to see this particular activation). I have made a label out of the activation in both cases and viewed it in the other space just to make sure that it is in fact the same activation, and it is. Any idea what might be going on? It seems to me that it can't be an issue with the BOLD volume --> structural volume registration, since the activations look normal on tkmedit. It seems to me, then, that it must have to do with the relationship between the anatomical volume and the anatomical surface--could this be where the problem lies? Maybe an imperfect surface reconstruction?

I've attached pictures of what I mean. The activation in question is in the right hemisphere. On the surface it can be seen on the medial part of the hemisphere , and in the volume it's where the red cursor is (as I mentioned, I verified by making labels that these are in fact the same activation).

Thank you very much,

JohnMark


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