Hi Richard, thanks for pointing this out – I’ll take a look into it.

best
Andrew

From: <freesurfer-boun...@nmr.mgh.harvard.edu> on behalf of "Jones, Richard" 
<richard.jo...@choa.org>
Reply-To: FS Help <freesurfer@nmr.mgh.harvard.edu>
Date: Thursday, April 19, 2018 at 9:49 AM
To: FS Help <freesurfer@nmr.mgh.harvard.edu>
Subject: [Freesurfer] Freesurfer dev version : recon all error mpr2mni305

I ran the command shown below to do recon-all on DICOM images from a Philips 
Ingenia scanner using the development version of freesurfer on a Mac running 
high Sierra.

recon-all -i /Users/Shared/HOPE_SS_Data/HOPE_SS020_Anat/IM-0001-0001.dcm 
-subject HOPE_SS020 –all

The program crashed with the error “ERROR: mpr2mni305 failed, see 
transforms/talairach_avi.log”

The talairach_avi.log file is shown below, followed by the log file. As a test 
I ran the same command, on the same data, using Freesurfer 6 and that ran 
without problems (except that it didn’t handle the diffusion tags in the 
Philips DICOM header correctly so I had to set FS_LOAD_DWI=0, this was not a 
problem in the development version). Any suggestions as to what may be causing 
the problems with the library in the development version?

Thanks,

Richard

/Applications/freesurfer_dev/subjects/HOPE_SS020/mri
/Applications/freesurfer_dev/bin/talairach_avi
--i orig_nu.mgz --xfm transforms/talairach.auto.xfm
$Id: FreeSurferEnv.csh,v 1.89 2016/06/09 14:54:31 zkaufman Exp $
Darwin meshuga.choa.org 17.5.0 Darwin Kernel Version 17.5.0: Mon Mar  5 
22:24:32 PST 2018; root:xnu-4570.51.1~1/RELEASE_X86_64 x86_64
Thu Apr 19 08:45:01 EDT 2018
mri_convert.bin orig_nu.mgz talsrcimg.img
$Id: mri_convert.c,v 1.227 2017/02/16 19:15:42 greve Exp $
reading from orig_nu.mgz...
TR=6.98, TE=3.14, TI=0.00, flip angle=8.00
i_ras = (-1, 7.45058e-09, 0)
j_ras = (3.72529e-09, -4.88944e-09, -1)
k_ras = (0, 1, 4.88944e-09)
writing to talsrcimg.img...
Analyze Output Matrix
-1.00000   0.00000   0.00000   128.15305;
0.00000  -0.00000   1.00000  -116.15433;
0.00000  -1.00000   0.00000   128.60870;
0.00000   0.00000   0.00000   1.00000;
--------------------
INFO: set hdr.hist.orient to -1
mpr2mni305 talsrcimg
Thu Apr 19 08:45:02 EDT 2018
/Applications/freesurfer_dev/bin/mpr2mni305 talsrcimg
$Id: mpr2mni305,v 1.5 2015/12/18 23:56:21 zkaufman Exp $
target=711-2C_as_mni_average_305

---------------------------------------------------------------------
analyzeto4dfp talsrcimg -O0 -y
---------------------------------------------------------------------

$Id: ifh2hdr.c,v 1.3 2007/05/05 10:45:03 nicks Exp $
Thu Apr 19 08:45:02 2018
Writing: talsrcimg.4dfp.hdr
$Id: analyzeto4dfp.c,v 1.2 2007/05/05 00:00:06 nicks Exp $
Reading: talsrcimg.hdr
header size 348 bytes
hdr.dime.datatype          offset=70            value=2
hdr.dime.bitpix                 offset=72            value=8
hdr.hist.orient                   offset=252          value=-1
dimensionality     4
dimensions       256       256       256         1
Reading: talsrcimg.img
Writing: talsrcimg.4dfp.img
Writing: talsrcimg.4dfp.ifh
ifh2hdr talsrcimg -r0to255
ori=2

---------------------------------------------------------------------
gauss_4dfp talsrcimg 1.1
---------------------------------------------------------------------

dyld: Library not loaded: /usr/local/opt/gcc/lib/gcc/7/libgfortran.4.dylib
  Referenced from: /Applications/freesurfer_dev/bin/gauss_4dfp
  Reason: image not found
Abort
ERROR: 'gauss_4dfp talsrcimg 1.1' failed! status=134
ERROR: mpr2mni305 execution aborted


Subject Stamp: freesurfer-darwin-OSX-ElCapitan-dev-20180415-0d56499
Current Stamp: freesurfer-darwin-OSX-ElCapitan-dev-20180415-0d56499
INFO: SUBJECTS_DIR is /Applications/freesurfer_dev/subjects
Actual FREESURFER_HOME /Applications/freesurfer_dev
Darwin meshuga.choa.org 17.5.0 Darwin Kernel Version 17.5.0: Mon Mar  5 
22:24:32 PST 2018; root:xnu-4570.51.1~1/RELEASE_X86_64 x86_64
/Applications/freesurfer_dev/subjects/HOPE_SS020
\n mri_convert /Users/Shared/HOPE_SS_Data/HOPE_SS020_Anat/IM-0001-0001.dcm 
/Applications/freesurfer_dev/subjects/HOPE_SS020/mri/orig/001.mgz \n
mri_convert.bin /Users/Shared/HOPE_SS_Data/HOPE_SS020_Anat/IM-0001-0001.dcm 
/Applications/freesurfer_dev/subjects/HOPE_SS020/mri/orig/001.mgz
$Id: mri_convert.c,v 1.227 2017/02/16 19:15:42 greve Exp $
reading from /Users/Shared/HOPE_SS_Data/HOPE_SS020_Anat/IM-0001-0001.dcm...
Starting DICOMRead2()
dcmfile = /Users/Shared/HOPE_SS_Data/HOPE_SS020_Anat/IM-0001-0001.dcm
dcmdir = /Users/Shared/HOPE_SS_Data/HOPE_SS020_Anat
Ref Series No = 301
Found 202 files, checking for dicoms
Found 200 dicom files in series.
First Sorting
Computing Slice Direction
Vs: -0.897217 -0.0611658 0.0354633
Vs: -0.996909 -0.0679621 0.0394038
Second Sorting
IsDWI = 0, IsPhilipsDWI = 0
Counting frames
nframes = 1
nslices = 200
ndcmfiles = 200
PE Dir = ROW (dicom read)
Loading pixel data
TR=6.98, TE=3.14, TI=0.00, flip angle=8.00
i_ras = (0.0644896, -0.994415, 0.0835493)
j_ras = (0.0448617, -0.08075, -0.995724)
k_ras = (0.996909, 0.0679621, 0.0394038)
writing to /Applications/freesurfer_dev/subjects/HOPE_SS020/mri/orig/001.mgz...
#--------------------------------------------
#@# MotionCor Thu Apr 19 08:44:06 EDT 2018
Found 1 runs
/Applications/freesurfer_dev/subjects/HOPE_SS020/mri/orig/001.mgz
Checking for (invalid) multi-frame inputs...
Only one run found so motion
correction will not be performed. I'll
copy the run to rawavg and continue.
\n cp /Applications/freesurfer_dev/subjects/HOPE_SS020/mri/orig/001.mgz 
/Applications/freesurfer_dev/subjects/HOPE_SS020/mri/rawavg.mgz \n
/Applications/freesurfer_dev/subjects/HOPE_SS020
\n mri_convert /Applications/freesurfer_dev/subjects/HOPE_SS020/mri/rawavg.mgz 
/Applications/freesurfer_dev/subjects/HOPE_SS020/mri/orig.mgz --conform \n
mri_convert.bin /Applications/freesurfer_dev/subjects/HOPE_SS020/mri/rawavg.mgz 
/Applications/freesurfer_dev/subjects/HOPE_SS020/mri/orig.mgz --conform
$Id: mri_convert.c,v 1.227 2017/02/16 19:15:42 greve Exp $
reading from /Applications/freesurfer_dev/subjects/HOPE_SS020/mri/rawavg.mgz...
TR=6.98, TE=3.14, TI=0.00, flip angle=8.00
i_ras = (0.0644896, -0.994415, 0.0835493)
j_ras = (0.0448617, -0.08075, -0.995724)
k_ras = (0.996909, 0.0679621, 0.0394038)
changing data type from short to uchar (noscale = 0)...
MRIchangeType: Building histogram
Reslicing using trilinear interpolation
writing to /Applications/freesurfer_dev/subjects/HOPE_SS020/mri/orig.mgz...
\n mri_add_xform_to_header -c 
/Applications/freesurfer_dev/subjects/HOPE_SS020/mri/transforms/talairach.xfm 
/Applications/freesurfer_dev/subjects/HOPE_SS020/mri/orig.mgz 
/Applications/freesurfer_dev/subjects/HOPE_SS020/mri/orig.mgz \n
INFO: extension is mgz
#--------------------------------------------
#@# Talairach Thu Apr 19 08:44:12 EDT 2018
/Applications/freesurfer_dev/subjects/HOPE_SS020/mri
\n mri_nu_correct.mni --no-rescale --i orig.mgz --o orig_nu.mgz --n 1 
--proto-iters 1000 --distance 50 \n
/Applications/freesurfer_dev/subjects/HOPE_SS020/mri
/Applications/freesurfer_dev/bin/mri_nu_correct.mni
--no-rescale --i orig.mgz --o orig_nu.mgz --n 1 --proto-iters 1000 --distance 50
nIters 1
$Id: FreeSurferEnv.csh,v 1.89 2016/06/09 14:54:31 zkaufman Exp $
Darwin meshuga.choa.org 17.5.0 Darwin Kernel Version 17.5.0: Mon Mar  5 
22:24:32 PST 2018; root:xnu-4570.51.1~1/RELEASE_X86_64 x86_64
Thu Apr 19 08:44:12 EDT 2018
Program nu_correct, built from:
Package MNI N3, version 1.12.0, compiled by ni...@gust.nmr.mgh.harvard.edu 
(x86_64-apple-darwin11.4.2) on 2015-06-19 at 15:37:08
/usr/bin/bc
tmpdir is ./tmp.mri_nu_correct.mni.9696
/Applications/freesurfer_dev/subjects/HOPE_SS020/mri
mri_convert orig.mgz ./tmp.mri_nu_correct.mni.9696/nu0.mnc -odt float
mri_convert.bin orig.mgz ./tmp.mri_nu_correct.mni.9696/nu0.mnc -odt float
$Id: mri_convert.c,v 1.227 2017/02/16 19:15:42 greve Exp $
reading from orig.mgz...
TR=6.98, TE=3.14, TI=0.00, flip angle=8.00
i_ras = (-1, 7.45058e-09, 0)
j_ras = (3.72529e-09, -4.88944e-09, -1)
k_ras = (0, 1, 4.88944e-09)
changing data type from uchar to float (noscale = 0)...
writing to ./tmp.mri_nu_correct.mni.9696/nu0.mnc...
--------------------------------------------------------
Iteration 1 Thu Apr 19 08:44:14 EDT 2018
nu_correct -clobber ./tmp.mri_nu_correct.mni.9696/nu0.mnc 
./tmp.mri_nu_correct.mni.9696/nu1.mnc -tmpdir ./tmp.mri_nu_correct.mni.9696/0/ 
-iterations 1000 -distance 50
[fs...@meshuga.choa.org:/Applications/freesurfer_dev/subjects/HOPE_SS020/mri/] 
[2018-04-19 08:44:14] running:
  /Applications/freesurfer_dev/mni/bin/nu_estimate_np_and_em -parzen -log 
-sharpen 0.15 0.01 -iterations 1000 -stop 0.001 -shrink 4 -auto_mask -nonotify 
-b_spline 1.0e-7 -distance 50 -quiet -execute -clobber -nokeeptmp -tmpdir 
./tmp.mri_nu_correct.mni.9696/0/ ./tmp.mri_nu_correct.mni.9696/nu0.mnc 
./tmp.mri_nu_correct.mni.9696/nu1.imp

Processing:.................................................................Done
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Processing:.................................................................Done
Number of iterations: 55
CV of field change: 0.000965325


mri_convert ./tmp.mri_nu_correct.mni.9696/nu1.mnc orig_nu.mgz --like orig.mgz 
--conform
mri_convert.bin ./tmp.mri_nu_correct.mni.9696/nu1.mnc orig_nu.mgz --like 
orig.mgz --conform
$Id: mri_convert.c,v 1.227 2017/02/16 19:15:42 greve Exp $
reading from ./tmp.mri_nu_correct.mni.9696/nu1.mnc...
TR=0.00, TE=0.00, TI=0.00, flip angle=0.00
i_ras = (-1, 7.45058e-09, 0)
j_ras = (3.72529e-09, -4.88944e-09, -1)
k_ras = (0, 1, 4.88944e-09)
INFO: transform src into the like-volume: orig.mgz
changing data type from float to uchar (noscale = 0)...
MRIchangeType: Building histogram
writing to orig_nu.mgz...

Thu Apr 19 08:45:01 EDT 2018
mri_nu_correct.mni done
\n talairach_avi --i orig_nu.mgz --xfm transforms/talairach.auto.xfm \n
talairach_avi log file is transforms/talairach_avi.log...
ERROR: mpr2mni305 failed, see transforms/talairach_avi.log


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