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We're attempting to get some reconstructions on MRI's for very advanced alzheimer's subjects. Many of these subjects have pretty extensive motion artifacts in their acquisitions. There has been some work with the so-called BLADE sequences to eliminate motion. Indeed, some of the blade sequences produce fairly good contrast. But these acquisitions have slices that aren't normalized for brightness and I think this complicates the reconstruction--see ( https://imgur.com/ZWhBlcm ) for an example. It seems like we should be able to perform some kind of slice-wise normalization to fix this, but I can't see a good way to do that with the freesurfer tools. Any advice would be greatly appreciated! Quentin Funk, PhD Houston Methodist Research Institute 713-363-9003<tel:713-363-9003> Houston Methodist. Leading Medicine. Houston Methodist is ranked by U.S. News & World Report as the No. 1 hospital in Texas and among the top 20 hospitals nationwide. Houston Methodist is the only nationally ranked Honor Roll hospital in the state and is designated as a Magnet hospital for excellence in nursing. houstonmethodist.org | twitter.com/MethodistHosp | facebook.com/HoustonMethodist ***CONFIDENTIALITY NOTICE*** This e-mail is the property of Houston Methodist and/or its relevant affiliates and may contain restricted and privileged material for the sole use of the intended recipient(s). Any review, use, distribution or disclosure by others is strictly prohibited. If you are not the intended recipient (or authorized to receive for the recipient), please contact the sender and delete all copies of the message. Thank you.
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