I assume you mean on an ROI basis. They are usually correlated in some
way because volume = thickness*area. The only way they could not be
correlated is if the area were to change opposite to thickness -- but
almost always they are both moving in the same direction, down:(
On 1/25/2023 10:25 AM, John Anderson wrote:
External Email - Use Caution
Dear experts,
this is the first time I have used Freesurfer. I am a clinician and I
don't have previous experience. I followed wiki instructions. I have a
group of T1 images. I need cortical thickness and cortical gray matter
volume measurements . I ran "recon-all" and I got all the measurements.
My question is about cortical thickness and cortical gray matter
volume, are these two measurements have to be correlated everytime? Is
it possible to find cases of cortical thinning and normal cortical
gray matter volume? I don't have a solid mathematical background. I am
wondering if those two numbers must always correlate with each other,
otherwise I am worried that an error in the analysis may lead to
cortical thinning and normal cortical gray matter volume.
Thank you for your time,
John
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