While it isn't bulletproof yet (restarting jobs that fail due to spot instance 
reclaims, etc), Cloudman (usegalaxy.org/cloud) does currently have support for 
running worker nodes as spot instances.  When you go to add nodes, just click 
"Use Spot Instances", and add your spot price.

For obvious reasons, you wouldn't want the head node of your cluster to be a 
spot instance, use a normal one for that.

-Dannon

On Jan 18, 2013, at 11:58 AM, Andrew Norman <anorma...@gmail.com> wrote:

> 
> Does anyone have any experience running Galaxy using Amazon's EC2 spot 
> pricing? It seems like that could save a lot of money as compared to 
> on-demand pricing, and it appears that there are ways to mix on-demand and 
> spot instances within one processing cluster:
> 
> http://aws.amazon.com/ec2/spot-and-science/
> 
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