These are options we'd like to add to Cufflinks, and I've created a Trello card 
for this enhancement:

https://trello.com/c/U7nceKdj

I want to add that community contributions via patch or pull request are highly 
encouraged and are likely to be quicker than waiting for the core team to get 
to this issue.

Best,
J.

On May 29, 2013, at 8:47 AM, Nikolay N. wrote:

> Hi,
> 
> Most people using the RNA-Seq toolkit use a combination of 
> Tophat/Cufflinks/Cuffdiff. A known issue is that cufflinks and cuffdiff use 
> different normalisation schemes 
> (http://seqanswers.com/forums/archive/index.php/t-26041.html). Users overcome 
> this problem by running cufflinks with the following flags:
> 
> --compatible-hits-norm --max-frag-multihits 1
> 
> However, in galaxy it is not possible to run cufflinks with these flags. Can 
> you, perhaps, add support for them?
> 
> many thanks,
> Nikolay
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