https://gcc.gnu.org/bugzilla/show_bug.cgi?id=109951
--- Comment #8 from Iain Sandoe <iains at gcc dot gnu.org> --- (In reply to Thomas Schwinge from comment #6) > <https://inbox.sourceware.org/875y868a4b....@euler.schwinge.homeip.net> > "Consider '--with-build-sysroot=[...]' for target libraries' build-tree > testing (instead of build-time 'CC' etc.) [PR109951]". this fixes the problem for me; I tried both a 64b host with a 32b multilib and vice versa. (smoke tested a couple more test suites, including Ada, with no apparent issues) However, my configuration does not have --with-build-sysroot= so that aspect is untested by me. (it is not an option used often on Darwin because of problems elsewhere in the configuration).