https://gcc.gnu.org/bugzilla/show_bug.cgi?id=111715
--- Comment #3 from Richard Biener <rguenth at gcc dot gnu.org> --- Reduced testcase: struct B { struct { int len; } l; long n; }; struct A { struct B elts[8]; }; static void set_len (struct B *b, int len) { b->l.len = len; } static int get_len (struct B *b) { return b->l.len; } int foo (struct A *a, int i, long *q) { set_len (&a->elts[i], 1); *q = 2; return get_len (&a->elts[i]); } with the patch we end up doing the following in FRE1. I think the path based disambiguation is unaffected by assigning a different alias set. int foo (struct A * a, int i, long int * q) { int D.2787; - int _9; <bb 2> : MEM <struct A> [(struct B *)a_3(D)].elts[i_4(D)].l.len = 1; *q_7(D) = 2; - _9 = MEM <struct A> [(struct B *)a_3(D)].elts[i_4(D)].l.len; - return _9; + return 1;