Dear UCSC
I am struggling with liftover on a local installation to convert from  
cow UMD3 to cow Bta4.
I have downloaded the program and the over chain files.
I have an input file with 11 million lines in tab separated format  
(chr, start, end id) called boranMD3.bed:
20      25320   25320   0
20      38034   38034   1
20      46945   46945   2
20      60000   60000   3
20      67502   67502   4
20      67848   67848   5
20      73108   73108   6
20      76763   76763   7
20      76768   76768   8

I run the command
./liftOver boranMD3.bed bosTauMd3ToBosTau4.over.chain boranBt4.bed  
boranUnmapped.bed

On completion boranBt4.bed is empty and boranUnmapped.bed has all 11  
million lines with the comment "Deleted in New".
I have tried on the website (original assembly: Aug 2009 (UMD3); new  
assembly: Oct 2007) with the first 12 lines of data and that gives the  
same result. Also on the website I have tried adding a "chr" prefix to  
the chromosome name ie chr20 but that did not work and I have tried  
reducing the ratio of bases that must remap to 0.1. All these fail  
with the same error for each line: "Deleted in New". I also tried  
using a single space as a delimiter but it complained that it was not  
in BED format.

Any idea what I might be doing wrong?

Thanks

Harry


Harry Noyes
Room 231 BioSciences Building
University of Liverpool
Crown Street
Liverpool
L69 7ZB
0151 795 4512
www.genomics.liv.ac.uk/tryps


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