Dear all,

I am trying to retrieve human mrna genomic intervals from the UCSC table
browser (whole genome).
I have noticed that the same mrna can be located on different genomic
regions depending on the search you perform on the table browser.
Two examples:

*The AK310762 mrna*

*Search 1:*
clade: Mammal
genome: Human
assembly: GRCh37
group: All Tables
database: hg19
table: kgXref
region: position AK310762
*results in: *


 SIZE IDENTITY CHROMOSOME STRAND  START     END       cDNA   START  END  TOTAL
------------------------------------------------------------------------------
 1352  100.0%         19     +  47105328  47113252  AK310762    23
1374  1375 
<http://genome.ucsc.edu/cgi-bin/hgTables?position=chr19:47105328-47113252&all_mrna=pack&hgsid=152164491>


*Search 2:*
clade: Mammal
genome: Human
assembly: GRCh37
group: All Tables
database: hg19
table: kgXref
region: genome
output format: select fields from primary and related tables
selected fields:
     hg19.kgXref.mRNA
     hg19.refGene.chrom
     hg19.refGene.strand
     hg19.refGene.txStart
     hg19.refGene.txEnd
*the AK310762 mrna **appears in the output as:*

hg19.kgXref.mRNA hg19.refGene.chrom hg19.refGene.strand
hg19.refGene.txStart hg19.refGene.txEnd
AK310762        chr14   +       90863326        90874617




*The CR607619 mrna*

*Search 1:*
clade: Mammal
genome: Human
assembly: GRCh37
group: All Tables
database: hg19
table: kgXref
region: position CR607619
*results in: *

 SIZE IDENTITY CHROMOSOME STRAND  START     END       cDNA   START  END  TOTAL
------------------------------------------------------------------------------
 1342  100.0%          7     -   5566815   5568363  CR607619     1
1342  1343 
<http://genome.ucsc.edu/cgi-bin/hgTables?position=chr7:5566815-5568363&all_mrna=pack&hgsid=152164491>

*Search 2:*
clade: Mammal
genome: Human
assembly: GRCh37
group: All Tables
database: hg19
table: kgXref
region: genome
output format: select fields from primary and related tables
selected fields:
     hg19.kgXref.mRNA
     hg19.refGene.chrom
     hg19.refGene.strand
     hg19.refGene.txStart
     hg19.refGene.txEnd
*the CR607619* *mrna **appears in the output as:*

hg19.kgXref.mRNA hg19.refGene.chrom hg19.refGene.strand
hg19.refGene.txStart hg19.refGene.txEnd
CR607619        chr17   -       79476998        79479827


I have checked the actual locations for both AK310762 and CR607619
mRNAs in the UCSC Genome browser.
It seems that the actual positions for both mRNAs are those obtained
in Searches 1.
Therefore, it seems that there is a problem in linking the tables
kgXref and refGene.

I would be very grateful if someone could check this question and
propose any solution for it.

Best wishes,

Jorge
_______________________________________________
Genome maillist  -  [email protected]
https://lists.soe.ucsc.edu/mailman/listinfo/genome

Reply via email to