Hello Vamsi,

Unfortunately, the coordinates for transcript mappings cannot be created 
to mirror those at NCBI. The alignments in the UCSC Genome browser are 
independently generated when the track is created (see the track 
description for the full methods).

One option for you is to download the NCBI coordinates yourself and 
create a custom track. This could be loaded back into the UCSC Browser 
and viewed along with the rest of our annotation.

Custom track help:
http://genome.ucsc.edu/goldenPath/help/hgTracksHelp.html#CustomTracks

Our apologies for the inconvenience. But, we hope this information is 
helpful.  Please feel free to contact the help mailing list again if you 
require further assistance.

Best regards,
Jen

UCSC Genome Browser Support
http://genome.ucsc.edu/contacts.html
[email protected]
[email protected]

On 6/11/10 3:45 AM, Vamsi Veeramachaneni wrote:
> Hi,
>
> I downloaded the hg19 refFlat.txt.gz file from UCSC 
> (ftp://genome-ftp.cse.ucsc.edu/goldenPath/hg18/database/refFlat.txt.gz). It 
> has multiple lines for a single gene. For instance, the command:
>
>     % grep -e DEFB106A -e DEFB106B refFlat.txt
>
> generates the four lines:
>
> DEFB106A        NM_152251       chr8    -       7340025 7343909 7340125 
> 7343904 2       7340025,7343855,        7340274,7343909,
> DEFB106A        NM_152251       chr8    +       7682693 7686575 7682698 
> 7686475 2       7682693,7686326,        7682747,7686575,
> DEFB106B        NM_001040704    chr8    -       7340025 7343909 7340125 
> 7343904 2       7340025,7343855,        7340274,7343909,
> DEFB106B        NM_001040704    chr8    +       7682693 7686575 7682698 
> 7686475 2       7682693,7686326,        7682747,7686575,
>
> In other words, DEFB106A and DEFB106B have exactly the same annotation. I 
> realize this is because of duplicate regions, but the co-ordinates at NCBI 
> are:
>   * DEFB106A as Chromosome 8 (7682694..7686575)
>   * DEFB106B as Chromosome 8 (7340026..7343909, complement)
>
> Is there any way of getting the refFlat file with only the NCBI version of 
> the gene co-ordinates (or as close to those coordinates as possible) ?
>
> Thanks,
> Vamsi
>
> _______________________________________________
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