Hello,

I have been running into problems with the liftover tool output.  I am
submitting SNPs from WGS to liftover to convert from hg19 to hg18 positions,
and around 1% map back incorrectly to the hg 18 position.  For example, on
chromosome 6 a large number of SNPs are mapped back to chromosome 3, 15 and
to chr6_random.  Has anyone ever noticed a problem like this before?  Any
insight into what could be happening here would be greatly appreciated.

Thanks,

Kian Preston-Suni
Dept. of Internal Medicine and Molecular Genetics
University of Michigan Medical School
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