Dear Anyuan,

The data in the ENCODE Regulation Txn Factor ChIP Track is only a subset of the 
data included HAIB TFBS and Yale TFBS tracks. The HAIB TFBS and Yale TFBS 
tracks contain additional views such as "Raw Signal" and "Signal" whereas the 
Txn Factor ChIP Track utilizes data from only the "Peaks" view from the those 
tracks.

If you have further questions, please contact the mailing list.

Vanessa Kirkup Swing
UCSC Genome Bioinformatics Group 


Subject:
inquire about UCSC Chip-seq data
From:
郭安源 <[email protected]>
Date:
Thu, 09 Dec 2010 10:49:09 +0800
To:
[email protected]

Dear sir,
Thanks for your great work about UCSC genome browser.
I have a question about the human Chip-Seq data.
At human hg18, under "Regulation" super tracks,there are tracks named "ENCODE
Integrated Regulation Tracks-Txn Factor ChIP", "HAIB TFBS", "Yale TFBS". I want
to know that whether the data in "ENCODE Integrated Regulation Tracks-Txn Factor
ChIP" contains all the data in tracks "HAIB TFBS" and "Yale TFBS". Since I saw
the following words on the track pages
http://genome.ucsc.edu/cgi-bin/hgTrackUi?hgsid=174800793&c=chr1&g=wgEncodeRegTfbsClustered
http://genome.ucsc.edu/cgi-bin/hgTrackUi?hgsid=174800793&c=chr1&g=wgEncodeHudsonalphaChipSeq
http://genome.ucsc.edu/cgi-bin/hgTrackUi?hgsid=174800793&c=chr1&g=wgEncodeYaleChIPseq
So if want a complete chip-seq data, need I download all these or just the Txn
Factor ChIP track?

Thanks very much.

Anyuan Guo

Description

This track shows regions where transcription factors, proteins responsible for
modulating gene transcription, bind to DNA as assayed by ChIP-seq (chromatin
immunoprecipitation with antibodies specific to the transcription factor
followed by sequencing of the precipitated DNA). Additional views of this data
set and additional documentation on the methods used for this track are
available at the Yale TFBS Track
<http://genome.ucsc.edu/cgi-bin/hgTrackUi?g=wgEncodeYaleChIPseq> and the HAIB
TFBS Track
<http://genome.ucsc.edu/cgi-bin/hgTrackUi?g=wgEncodeHudsonalphaChipSeq> pages.
The /Peaks / views in those pages are the basis for the clusters shown here,
which combine data from the peaks from the different cell lines and different
transcription factors in those pages.

Credits

This track shows data from the Myers Lab <http://myers.hudsonalpha.org/> at the
HudsonAlpha Institute for Biotechnology <http://www.hudsonalpha.org/> and by the
labs of Michael Snyder <http://snyderlab.stanford.edu/>, Mark Gerstein
<http://bioinfo.mbb.yale.edu/> and Sherman Weissman
<http://info.med.yale.edu/bcmm/SMW/SMWhome2.html> at Yale University; Peggy
Farnham <http://www.genomecenter.ucdavis.edu/farnham/> at UC Davis; and Kevin
Struhl <http://struhl.med.harvard.edu/> at Harvard.

On the HAIB TFBS page, it shows "These data were provided by the Myers Lab
<http://myers.hudsonalpha.org/> at the HudsonAlpha Institute for Biotechnology
<http://www.hudsonalpha.org/>.".
On the Yale TFBS track page, it shows "These data were generated and analyzed by
the labs of Michael Snyder <http://www.yale.edu/snyder/>, Mark Gerstein
<http://bioinfo.mbb.yale.edu/> and Sherman Weissman
<http://info.med.yale.edu/bcmm/SMW/SMWhome2.html> at Yale University; Peggy
Farnham <http://www.genomecenter.ucdavis.edu/farnham/> at UC Davis; and Kevin
Struhl <http://struhl.med.harvard.edu/> at Harvard. Contact: the Gerstein lab
<mailto:[email protected]>. ".

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