Good Afternoon Sri:

You can run phylop on any alignment you create:

http://compgen.bscb.cornell.edu/phast/help-pages/phyloP.txt

--Hiram

Srirangan Sampath wrote:
> Hello,
>         How can one generate PhyloP values for only a few species (entire 
> genome) ...say
 > Human, Chimp, Orangutan and Rhesus...instead of relying on the PhyloP values 
 > for 44
> or 46 species (that includes Primate, placental mammals, and vertebrates 
> species)
> that can be downloaded from UCSC website? This is because genome sequences of 
> some
> species are bad and including them in the PhyloP calculation could lead to 
> bias. 
> Thank you.
> 
> Sri.
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