Hi, I am trying to look for regions that are conserved in the human genome. I see several options. I am trying to interpret the scores that come with each option used. For eg, I used the 44-species alignement and this is an example output
1347 chr10 100003294 100003484 28916644 8575806112 0.7316 1347 chr10 100003484 100003547 28916644 8575826654 0.727194 1347 chr10 100003547 100003576 28916644 8575836655 0.36254 1347 chr10 100003576 100003594 28916644 8575846077 0.439916 1347 chr10 100003594 100003625 28916644 8575853175 0.465818 1347 chr10 100003625 100003672 28916644 8575860760 0.487689 1347 chr10 100003672 100003717 28916644 8575869528 0.513651 The last column is the overall score. CAn you give me a rough rule of thumb as to how to interpret these scores. I probably need to read about Phastcons and PhyloP to get a better understanding of what the different conservation tracks are, but if you can give me some idea about the 44-way alignment, I will appreciate it. Many thanks. Best, Suganthi Yale University _______________________________________________ Genome maillist - [email protected] https://lists.soe.ucsc.edu/mailman/listinfo/genome
