Dear UCSC, I want to check whether my sequence is conserved in Mammal or not.
I am using Human conservation track and Mammal Cons (phastCons46wayPlacental) table on ucsc. I download the data and each point have a score. In describe of ucsc, it said that "the phastCons scores, by contrast, represent probabilities of negative selection and range between 0 and 1." But I do not understand what it this mean. If the phastCons scores is high (e.g. 1.0), does this mean that this site is conserved? Or does this mean this site have a high substitution? Thank you very much for your time. The data is like fellow: variableStep chrom=chr10 span=1 102746256 0 102746257 0 102746258 0 102746259 0.015748 102746260 0.015748 102746261 0.0314961 102746262 0.0472441 102746263 0.015748 _______________________________________________ Genome maillist - [email protected] https://lists.soe.ucsc.edu/mailman/listinfo/genome
