I have identified several regions of the dog genome (the regions are bounded each by 2 BACs) I'm interested in translating to the human genome. I've used the convert function using the end read coordinates for the BACs proximal and distal to the regions of interest, however, as far as I know the BACs have not been fully sequenced. I have some questions: The end reads are available for each BAC, is the "between" sequence available? I'm trying to find orthologous regions in human compared to dog and in some cases, the regions span a breakpoint in synteny between the species. According to the Ensembl synteny feature, I have a general idea of which parts of dog chromosomes are orthologous to which parts of human chromosomes. However, I'm not sure how to identify specific coordinates for the breakpoint in synteny. Thanks for any help you can provide!
Shannon Becker [email protected] PhD candidate Comparative Biomedical Sciences College of Veterinary Medicine North Carolina State University http://publicationslist.org/shannon.becker http://www.breenlab.org _______________________________________________ Genome maillist - [email protected] https://lists.soe.ucsc.edu/mailman/listinfo/genome
