Hi Monica, Sorry for the delayed reply. I think this other recent mailing list question should also answer your questions:
=> https://lists.soe.ucsc.edu/pipermail/genome/2011-June/026343.html This paper all discusses how some of the reasons why you will see genes "migrate" between assemblies: => http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0021400 Please let us know if you have any additional questions: [email protected] - Greg Roe UCSC Genome Bioinformatics Group On 7/12/11 2:38 PM, Monica Garcia-Espino wrote: > My name is Monica L. Garcia Espino and I have been studying an specific > gene(DSCAM) in the human genome which is located in the Down syndrome > Critical Region, and looking at the databases of UCSC I found out that > the location of the DSCAM gene has changed location from > 2006(NCBI36/hg18) and the current 2009(GRCh37/hg19). In 2006 the > location of this gene is at 40,306213 and it moved around 1 million bp > starting at 41,308343 in 2009. I don’t understand how the gene could've > change location in the human genome and why it moves? how can I know > that the data that I am obtaining is valid? Could you please help me to > understand more about these gene models? > > Thank you. > _______________________________________________ > Genome maillist - [email protected] > https://lists.soe.ucsc.edu/mailman/listinfo/genome _______________________________________________ Genome maillist - [email protected] https://lists.soe.ucsc.edu/mailman/listinfo/genome
