Hello Rico,

This problem has been looked at before on the mailing list. Please see 
this previously answered question thread for further advice:

https://lists.soe.ucsc.edu/pipermail/genome/2011-September/027213.html

Hopefully this information was helpful and answers your question. If you 
have further questions or require clarification feel free to contact the 
mailing list at [email protected].

Regards,

Pauline Fujita
UCSC Genome Bioinformatics Group
http://genome.ucsc.edu


On 11/23/11 1:54 AM, Richard Burhans wrote:
> Folks,
>
> While using wigToBigWig to convert the primate phyloP scores for the 44-way 
> alignment with hg18 to bigwig, I found several positions with multiple 
> scores.  Here are links to the files I was trying to convert:
>
>       
> http://hgdownload.cse.ucsc.edu/goldenPath/hg18/phyloP44way/primates/chr1.phyloP44way.primate.wigFix.gz
>       
> http://hgdownload.cse.ucsc.edu/goldenPath/hg18/phyloP44way/primates/chr2.phyloP44way.primate.wigFix.gz
>       
> http://hgdownload.cse.ucsc.edu/goldenPath/hg18/phyloP44way/primates/chr3.phyloP44way.primate.wigFix.gz
>       
> http://hgdownload.cse.ucsc.edu/goldenPath/hg18/phyloP44way/primates/chr4.phyloP44way.primate.wigFix.gz
>       
> http://hgdownload.cse.ucsc.edu/goldenPath/hg18/phyloP44way/primates/chr13.phyloP44way.primate.wigFix.gz
>       
> http://hgdownload.cse.ucsc.edu/goldenPath/hg18/phyloP44way/primates/chr16.phyloP44way.primate.wigFix.gz
>       
> http://hgdownload.cse.ucsc.edu/goldenPath/hg18/phyloP44way/primates/chrY.phyloP44way.primate.wigFix.gz
>
> Here's the problems I found along with proposed solutions:
>
>       o chr1
>               o more than one value for chr1 base 220000001
>               o suggest changing line 195836790 to "fixedStep chrom=chr1 
> start=220000002 step=1"
>
>       o chr2
>               o more than one value for chr2 base 60000001
>               o more than one value for chr2 base 230000001
>               o suggest changing line 59341383 to "fixedStep chrom=chr2 
> start=60000002 step=1"
>               o suggest changing line 222927573 to "fixedStep chrom=chr2 
> start=230000002 step=1"
>
>       o chr3
>               o more than one value for chr3 base 180000001
>               o suggest changing line 173437707 to "fixedStep chrom=chr3 
> start=180000002 step=1"
>
>       o chr4
>               o more than one value for chr4 base 110000001
>               o suggest changing line 104807632 to "fixedStep chrom=chr4 
> start=110000002 step=1"
>
>       o chr13
>               o more than one value for chr13 base 60000001
>               o suggest changing line 41706166 to "fixedStep chrom=chr13 
> start=60000002 step=1"
>
>       o chr16
>               o more than one value for chr16 base 20000001
>               o suggest changing line 19816949 to "fixedStep chrom=chr16 
> start=20000002 step=1"
>
>       o chrY
>               o more than one value for chrY base 20000001
>               o suggest changing line 16192938 to "fixedStep chrom=chrY 
> start=20000002 step=1"
>
> -rico
>       
>
>
>
>
>
>
> _______________________________________________
> Genome maillist  -  [email protected]
> https://lists.soe.ucsc.edu/mailman/listinfo/genome

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