dear all,

I am writing to you because I am not clear about the following 
statements about the liftOver utility: The important sentences in bold

The LiftOver <http://genome.ucsc.edu/cgi-bin/hgLiftOver> tool, accessed 
via the Utilities link on the Genome Browser home page, also supports 
forward, reverse, *and cross-species conversions, as well as batch 
conversions. *

If you wish to update a large number of coordinates to a different 
assembly and have access to a Linux platform, you may find it useful to 
try the command-line version of the LiftOver tool. *The executable file 
for this utility can be downloaded here 
<http://hgdownload.cse.ucsc.edu/admin/exe/>. LiftOver requires a 
UCSC-generated /over.chain/ file as input.* Pre-generated files are 
available for selected assemblies from the Downloads 
<http://hgdownload.cse.ucsc.edu/downloads.html#liftover> page. If the 
desired file is not available, send a request to the genome mailing list 
<http://genome.ucsc.edu/contacts.html> and we may be able to provide you 
with one.

Here is what I did: I downloaded the executable for the utility and the 
corresponding lift over chain file (*>>>* mm9 to hg19) and executed the 
script, however I am confused by the following hint within the man pages 
of the lift over utility :

***********************************************************************
*WARNING: liftOver was only designed to work between different
          assemblies of the same organism, it may not do what you want
          if you are lifting between different organisms.*
***********************************************************************

therefore can I convert coordinates cross species or not ?

cheers and as usual thanks in advance.

Carsten


_______________________________________________
Genome maillist  -  [email protected]
https://lists.soe.ucsc.edu/mailman/listinfo/genome

Reply via email to