This previous mailing list thread might also have some useful information:
https://lists.soe.ucsc.edu/pipermail/genome-mirror/2010-October/002139.html

On 12/16/11 2:39 PM, Greg Roe wrote:
> Hi Hongyu,
>
> We're pretty sure that the error you're getting is Ubuntu specific. 
> (Googling " ubuntu mysql connect socket" comes up with a lot of hits 
> with people having this issue.)
>
> Two things to try...
>
> Try to set db.socket as suggested here:
> https://lists.soe.ucsc.edu/pipermail/genome-mirror/2011-August/002722.html 
>
>
> If this does not work, try the "Problem 2" solution in this thread:
> https://lists.soe.ucsc.edu/pipermail/genome-mirror/2010-July/001949.html
>
>
> Please let us know if you have any additional questions: 
> [email protected]
>
> -
> Greg Roe
> UCSC Genome Bioinformatics Group
>
>
>
> On 12/12/11 11:31 PM, Hongyu Zhang wrote:
>> Hi Greg,
>>
>> the value of "socket" is
>>
>> | socket                                  | /var/run/mysqld/mysqld.sock
>>
>> Hongyu
>>
>> 2011/12/13 Greg Roe<[email protected]>
>>
>>> Hi Hongyu,
>>>
>>> Can you issue a "show variables;" command and let us know what is the
>>> value of "socket" displayed is?
>>>
>>> For example you may see something like:
>>>
>>> | socket | /var/lib/mysql/mysql.sock
>>>
>>>
>>> Please reply to:[email protected]
>>> -
>>> Greg Roe
>>> UCSC Genome Bioinformatics Group
>>>
>>>
>>>
>>> On 12/10/11 12:58 AM, Hongyu Zhang wrote:
>>>
>>>> Hi,
>>>>
>>>> I have installed the genome browser on my Ubuntu 11.10, I can access
>>>> the mysql in the terminal:
>>>>
>>>> mysql -ureadwrite -pupdate --socket /var/run/mysqld/mysqld.sock
>>>> mysql -ureadonly -paccess --socket /var/run/mysqld/mysqld.sock
>>>> mysql -ubrowser -pgenome --socket /var/run/mysqld/mysqld.sock
>>>>
>>>> But, when I access to the genome browser, the following error occurs:
>>>>
>>>> Couldn't connect to database (null) on localhost as readwrite. Can't
>>>> connect to local MySQL server through socket '/var/lib/mysql/mysql.sock'
>>>> (13)
>>>>
>>>>
>>>> The content of  hg.conf under cgi-bin list as follow:
>>>>
>>>> db.host=localhost
>>>> db.user=readonly
>>>> db.password=access
>>>>
>>>> db.socket=/var/run/mysqld/**mysqld.sock
>>>> db.port=3306
>>>>
>>>> defaultGenome=Human
>>>>
>>>> db.trackDb=trackDb
>>>>
>>>> db.grp=grp
>>>>
>>>> wiki.host=genomewiki.ucsc.edu
>>>> wiki.userNameCookie=wikidb_**mw1_UserName
>>>> wiki.loggedInCookie=wikidb_**mw1_UserID
>>>>
>>>> customTracks.host=<your specific host name>
>>>> customTracks.user=<your specific MySQL user for this function>
>>>> customTracks.password=<MySQL password for specified user>
>>>> customTracks.useAll=yes
>>>> customTracks.tmpdir=/data/tmp/**ct
>>>>
>>>> browser.indelOptions=on
>>>>
>>>> central.db=hgcentral
>>>> central.host=localhost
>>>>
>>>> central.user=readwrite
>>>> central.password=update
>>>> central.domain=mylab.**university.edu<http://mylab.university.edu>
>>>>
>>>> browser.background=../images/**floret.jpg
>>>>
>>>> browser.documentRoot=/usr/**local/apache/htdocs
>>>>
>>>> grepIndex.genbank=/data/tmp/**grepIndex
>>>> grepIndex.default=/gbdb
>>>>
>>>> backupcentral.db=hgcentral
>>>> backupcentral.host=localhost
>>>> backupcentral.user=readwrite
>>>> backupcentral.password=update
>>>>
>>>> archivecentral.db=hgcentral
>>>> archivecentral.host=localhost
>>>> archivecentral.user=readwrite
>>>> archivecentral.password=update
>>>>
>>>> hgc.psxyPath=/hive/data/**outside/GMT4.3.1/bin/psxy
>>>> hgc.ps2rasterPath=/hive/data/**outside/GMT4.3.1/bin/ps2raster
>>>> hgc.ghostscriptPath=/usr/bin/**ghostscript
>>>>
>>>> Could you please tell me what's the problem?
>>>>
>>>> Many thanks!
>>>>
>>>> Hongyu Zhang
>>>> Shanghai Cancer Institute
>>>> ______________________________**_________________
>>>> Genome-mirror mailing list
>>>> [email protected]
>>>> https://lists.soe.ucsc.edu/**mailman/listinfo/genome-mirror<https://lists.soe.ucsc.edu/mailman/listinfo/genome-mirror>
>>>>
>> _______________________________________________
>> Genome maillist  [email protected]
>> https://lists.soe.ucsc.edu/mailman/listinfo/genome
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