Hi Anna,

I was looking at this question again as part of the update we are doing 
on the UCSC Genes track.  With the latest build (not yet available), we 
made changes to our pipeline that fixed some naming issues.  However, 
this it turns out that this particular case did not have a naming 
problem, after all.

The names of UCSC Genes that you see in the kgXref table come from the 
associated RefSeq gene or UniProt protein if there is one, and from the 
GenBank mRNA name if not.  uc011dhu.1 is based on the CU674603 mRNA and 
does not have a supporting RefSeq gene or UniProt protein.  If you turn 
on the mRNA track, you will see the CU674603 mRNA aligned to this spot, 
and if you click through to the details page you will see that it is 
indeed named "TUBB2A."

You might want to take this annotation and its name with a grain of 
salt:  it is based only on a non-RefSeq transcript (and hence is colored 
light blue, see the UCSC Genes methods page: 
http://hgwdev.cse.ucsc.edu/cgi-bin/hgGene?hgg_do_kgMethod=1), and the 
description for CU674603 says it is a "Synthetic construct."  You should 
also know that GenBank mRNA names can only be changed by the original 
submitter of the transcript, so the names are not curated like RefSeq 
and UniProt names.

I hope this information is helpful.  If you have further questions, 
please contact us again at [email protected].

--
Brooke Rhead
UCSC Genome Bioinformatics Group


On 11/28/11 10:54 AM, Pauline Fujita wrote:
> Hello Anna,
>
> This is a known issue that we are working to fix in the next UCSC genes
> release.  We expect the release will be out in the near future.
>
> Best regards,
>
> Pauline Fujita
> UCSC Genome Bioinformatics Group
> http://genome.ucsc.edu
>
>
> On 11/7/11 1:42 AM, Antigoni Elefsinioti wrote:
>> Hi I am a postdoc student in MDC Berlin. I have a question regarding the
>> antisense gene with id uc011dhu.1 (+ strand, chr6:3,224,986-3,226,037).
>> in the kgXref table the Genesymbol name for this  id    is  TUBB2A.  But
>> TUBB2A corresponds to tubulin gene that is in minus strand in position
>> (chr6:3,153,904-3,157,783). Why do these two sequences have the same name?
>> best
>> Anna Elefsinioti
>>
>>
>> _______________________________________________
>> Genome maillist  -  [email protected]
>> https://lists.soe.ucsc.edu/mailman/listinfo/genome
> _______________________________________________
> Genome maillist  -  [email protected]
> https://lists.soe.ucsc.edu/mailman/listinfo/genome
_______________________________________________
Genome maillist  -  [email protected]
https://lists.soe.ucsc.edu/mailman/listinfo/genome

Reply via email to