Good afternoon Luvina,

I am a research mentor who is helping an undergrad with her project. Thank you 
very much for your generous assistance.

We have a question about your earlier instructions for finding promoter regions 
that overlap with histone methylation peaks (H3K27me3).

~~~ "To find the actual transcription start positions, you will need to query 
the knownCanonical table in the Table Browser (to get only one isoform). You 
will also need to filter by strand on the knownGene table by clicking on the 
'create' button next to 'filter:', and setting 'strand does match +' (for the 
positive strand)…"

Can you please clarify? Do we download the knownCanonical and knownGene tables 
separately and filter genes by hand, or is there a way to retrieve only the 
information from knownGenes that overlaps with knownCanonical?

Thank you,
---Karmella

--
Karmella A. Haynes, Ph.D.
Assistant Professor
School of Biological and Health Systems Engineering
Arizona State University
501 E. Tyler Mall, ECG 346
Tempe, AZ 85287
E-mail: [email protected]<mailto:[email protected]>
Website: haynes.lab.asu.edu

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