Hello, Frank,

We have a Restriction Enzyme track in the top track group
(Mapping and Sequencing Tracks) below the main Browser graphic.
If you click on the link, you will find a configuration page that
allows you to add just the enzymes of interest.

As you will read in the explanatory text on that page, the enzymes
you cite will not be displayed for windows < 20 kb because of the
density of the display.  Browsing around the genome with a 20 kb
window will give you a rough idea of the extent of digestion, however.

If you wish a more complete sense of the site density, you will
need to do some processing on your own.  The RE track is computed
on the fly for display in the Browser and there is no table of enzyme
sites to download.

The following previously answered question gives some information
on how you might get a complete list of the sites for your enzymes.

https://lists.soe.ucsc.edu/pipermail/genome/2006-October/011861.html

best wishes, and thanks for being Browser user.

                                --b0b kuhn
                                ucsc genome bioinformatics group


On 2/10/2012 10:17 AM, Martiniuk, Frank wrote:
> Dear UCSC,
> 
>    I am looking for a list of restriction sites and number of sites in the
> human genome.  I want to digest a sample that contains human DNA with some
> mycobacterial DNA.  Enzymes SWAI; PMEI and PACI very rarely cut the
> mycobacterial genome.  I need to know if any or all of these 3 enzymes will
> fragment the human DNA leaving large mycobacterial fragments.  Can you help.
> 
> Frank Martiniuk
> NYU School of Medicine
> 
> 
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