Hi Nahar, I spot checked a couple of the genes in your list and they seem ok. mRNA sequences can align to multiple places. The various homologous "copies" are not obligated to be on the same chromosome or the same strand. Various evolutionary mechanisms cause dna sections to be duplicated. The aligner finds them when they have a very high degree of homology.
If you have any additional questions, please reply to: [email protected] - Greg Roe UCSC Genome Bioinformatics Group On 3/19/12 5:50 AM, Dr.Rahul Nahar wrote: > Dear UCSC genome browser team > > I had downloaded the all Refseq genes from the table browser. I see that for > some Gene symbols, for the same Transcript ID (Refseq ID) there are separate > entries with both the strands ( + and -). What does this mean ? Is this gene > present on both strands ? Or is it just an error in the file. This is with > reference to GRCh37/hg19 assembly. > > I have attached the list of 276 genes which have this error. > > Please clarify. > > Thanks& Regards > -- > Rahul Nahar > > > ________________________________ > This e-mail contains PRIVILEGED AND CONFIDENTIAL INFORMATION intended solely > for the use of the addressee(s). If you are not the intended recipient, > please notify the sender by e-mail and delete the original message. Further, > you are not to copy, disclose, or distribute this e-mail or its contents to > any other person and any such actions that are unlawful. This e-mail may > contain viruses. Ocimum Biosolutions has taken every reasonable precaution to > minimize this risk, but is not liable for any damage you may sustain as a > result of any virus in this e-mail. You should carry out your own virus > checks before opening the e-mail or attachment. > > > The information contained in this email and any attachments is confidential > and may be subject to copyright or other intellectual property protection. If > you are not the intended recipient, you are not authorized to use or disclose > this information, and we request that you notify us by reply mail or > telephone and delete the original message from your mail system. > > OCIMUMBIO SOLUTIONS (P) LTD > > > _______________________________________________ > Genome maillist - [email protected] > https://lists.soe.ucsc.edu/mailman/listinfo/genome _______________________________________________ Genome maillist - [email protected] https://lists.soe.ucsc.edu/mailman/listinfo/genome
