Hi Peng,

Sorry for the confusion.  There was discussion of the -multiple option 
because it is something that *seems* like it might make liftOver work 
like you were hoping.  It does not.

liftOver was designed to convert coordinates in blocks by just mapping 
the start and the end coordinates.  It does not have capabilities to do 
base-by-base conversions.  You might want to check out the pslMap tool 
instead.  Here is a previously-answered question on the topic of pslMap 
that should be helpful:

https://lists.soe.ucsc.edu/pipermail/genome/2008-March/015908.html

If you have further questions, please contact us again at 
[email protected].

--
Brooke Rhead
UCSC Genome Bioinformatics Group


On 6/14/12 6:40 PM, Peng Yu wrote:
>> One of our engineers has this to say: "-multiple really only means use
>> multiple best chains, but here we only have one chain, and one bed4 block,
>> and it just expands the interval until it is large enough." We have noted
>> your request.
>
> Hi Luvina,
>
> Thanks. But I don't get your point. I never used -multiple.
>
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