I forgot the slides. Sorry.
Glauber On Tue, Jun 19, 2012 at 1:12 PM, Glauber Brito <[email protected]>wrote: > Dear colleague, > > I downloaded human RefSeq genomic coordinates using the Table Browser tool > in order to identify bidirectional promoters. I checked some gene pairs > known to be in head-to-head configuration (less than 1000 bp apart). > Strangely a significant difference (~15-29 kb) was observed for these pairs > according to my calculations, which were basically finding genes in the > same chromosome and in opposite strands and having TSSs less than 1000 bp > apart, without overlapping. > > In fact, the Genome Browser showed these genes as regulated by > bidirectional promoters (head-to-head orientation), while the genomic > coordinates didn't. I attached somes slides depicting some of these flaws. > > Am I doing something wrong? > > I appreciate your help. > > > Cheers, > > Glauber > > > ---------------------------------------------- > Glauber C. Brito, PhD > Centro de Investigação Translacional em Oncologia > Instituto do Câncer do Estado de São Paulo > Faculdade de Medicina da Universidade de São Paulo > Av. Dr. Arnaldo, 251. Cerqueira César > CEP 01246-000 - São Paulo - SP - Brasil > Tel: + 55 11 38933007 >
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